sup {
  font-weight: 600;
  font-family: sans-serif;
}
.page-inner h2 {
  font-size: 72px;
  line-height: 69px;
  font-family: Sofia Pro;
  font-weight: 900;
  letter-spacing: 0.01px;
}
.page-inner h6 {
  font-family: "Raleway";
  font-size: 30px;
  font-weight: 700;
}
.page-inner p {
  font-family: Raleway;
  font-weight: 700;
  font-size: 22px;
  line-height: 35px;
  letter-spacing: 0px;
}

header .navbar-nav li.current-menu-item a.nav-link {
  border-bottom: 2px solid #159b80;
  color: #103f4e;
  padding-bottom: 6px;
}
.nuwiq-trials h2 {
  font-size: 58px;
  line-height: 66px;
  letter-spacing: -0.73px;
  color: #159b80;
  margin-bottom: 35px;
}
.nuwiq-trials p {
  color: #103f4e;
  margin: 0 0 30px;
  padding-right: 15px;
}

.nuwiq-trials-content {
  padding-top: 250px;
}
.nuwiq-trials .rotate-img {
  position: relative;
  z-index: 1;
  margin-top: 75px;
}
.nuwiq-trials .circle-one {
  width: 930px;
  height: 930px;
  top: -20%;
  left: -19%;
}
.nuwiq-trials .circle-two {
  width: 805px;
  height: 805px;
}
.nuwiq-trials .circle-three {
  width: 680px;
  height: 680px;
}
.nuwiq-trials {
  padding-bottom: 200px;
}

.completed-trials-section {
  margin: 100px 0 0;
}

.completed-trials h2 {
  line-height: 95px;
  color: #159b80;
  margin-bottom: 25px;
  text-align: center;
}

.completed-trials-content {
	background: url(../image/bg-grid-line.png) no-repeat;
	background-size: cover;
	padding: 0 108px;
	margin: 0 -108px 150px;
	padding-top: 15px;
	overflow-x: auto;
	overflow-y: hidden !important;
}
.completed-trials-content .year-btn {
  width: 80px;
  height: 80px;
  min-width: 80px;
  text-align: center;
  border-radius: 16px;
  align-items: center;
  justify-content: center;
  display: flex;
  background: #eaf3fa;
  color: #159b80;
  font-size: 24px;
  font-weight: 900;
  font-family: "Sofia Pro";
  box-shadow: -9px -9px 22px #fff, 9px 2px 35px rgba(18, 61, 101, 25%);
}
.completed-trials-content .flow-arrow img {
  max-width: 65px;
  margin: 0 auto;
}
.completed-trials-content .flow-arrow:last-child img {
  max-width: 22px;
}
.completed-trials-content .flow-arrow {
  padding: 0 18px;
}
.completed-trials-list .gradient {
  background: linear-gradient(90deg, #9cc643, #159b80);
  border-radius: 11px;
  color: #fff;
  font-size: 16px;
  line-height: 18px;
  font-weight: 600;
  font-family: Sofia Pro;
  padding: 10px 10px;
  text-align: center;
  box-shadow: 18px 30px 30px rgba(21, 155, 128, 17%);
}
.completed-trials-list {
	gap: 30px;
	display: flex;
	flex-direction: column;
	margin-top: 39px;
}
.completed-trials-list .small {
  width: 148px;
  min-width: 148px;
}

.completed-trials-list .medium {
  width: 224px;
  min-width: 224px;
}
.completed-trials-list .long {
  width: 100%;
  max-width: 571px;
  min-width: 571px;
}

.completed-trials-list .row1 {
  gap: 278px;
  padding-left: 108px;
}

.completed-trials-list .row2 {
  gap: 252px;
  padding-left: 137px;
}
.completed-trials-list .row3 {
  gap: 28px;
  padding-left: 258px;
}
.completed-trials-list .row4 {
  padding-left: 270px;
}
.completed-trials-list .row5 {
  padding-left: 273px;
  gap: 222px;
}
.completed-trials-list .row6 {
  padding-left: 700px;
}
.completed-trials-list .row2 .long {
  width: 314px;
  min-width: 314px;
}
.completed-trials-list .row5 .long {
  width: 571px;
}
.completed-trials-list .row6 .long {
  width: 472px;
  min-width: 472px;
}
.completed-trials-note {
  margin-top: 94px;
  padding-bottom: 42px;
}
.page-inner .completed-trials-note p {
  font-size: 12px;
  color: #95a6bf;
  font-weight: 500;
}

.completed-trials-section-dark .completed-trials-list .gradient {
  box-shadow: 18px 30px 30px rgba(2, 34, 27, 17%);
}

.completed-trials-section-dark {
  background: #103f4e;
  padding: 148px 0 155px;
}
.completed-trials-section-dark .completed-trials h2 {
  color: #dbdb27;
  margin: 0 0 54px;
}
.completed-trials-section-dark .completed-trials-content {
  background: url(../image/bg-grid-line-dark.png) no-repeat;
  background-size: cover;
  padding-top: 90px;
  margin: 0 -108px 38px;
}
.completed-trials-section-dark .completed-trials-content .year-btn {
  background: #144a5b;
  color: #dbd927;
  box-shadow: -8px -8px 20px #154c5c, 8px 2px 32px rgba(2, 8, 13, 52%);
}
.completed-trials-section-dark .completed-trials-content .flow-arrow img {
  filter: brightness(0) invert(1);
}

.completed-trials-section-dark .completed-trials-list .row1 .long {
  width: 100%;
  max-width: 1100px;
  display: flex;
  align-items: center;
  text-align: center;
}
.completed-trials-section-dark .completed-trials-list .long img {
  width: 42px;
  margin-right: 168px;
}
.completed-trials-section-dark .completed-trials-list .row1 {
  gap: 0px;
  padding-left: 226px;
}
.completed-trials-section-dark .completed-trials-list .row2 {
  gap: 0px;
  padding-left: 0px;
  margin-left: -15px;
}
.completed-trials-section-dark .completed-trials-list .row2 .long {
  max-width: 880px;
  width: 100%;
  text-align: center;
  justify-content: center;
  display: flex;
  align-items: center;
}
.completed-trials-section-dark .completed-trials-list a {
  color: #fff;
  text-decoration: none;
  cursor: pointer;
}
.completed-trials-section-dark .completed-trials-list .row3 {
  gap: 0px;
  padding-left: 424px;
}
.completed-trials-section-dark .completed-trials-list .row3 img {
  width: 42px;
  margin-right: 35px;
}
.completed-trials-section-dark .completed-trials-list .row3 .medium {
  width: 401px;
  align-items: center;
  justify-content: center;
  display: flex;
  background: linear-gradient(94.95deg, #fcfa53 0.88%, #dbd927 96.55%);
  color: #1e2f36;
}
.completed-trials-section-dark .completed-trials-list .row4 {
  gap: 0px;
  padding-left: 660px;
}
.completed-trials-section-dark .completed-trials-list .row4 .medium {
  width: 290px;
  align-items: center;
  justify-content: center;
  display: flex;
  min-width: 290px;
}
.completed-trials-section-dark .completed-trials-list .row4 img {
  width: 42px;
  margin-right: 78px;
}
.completed-trials-section-dark .completed-trials-list .row5 {
  gap: 0px;
  padding-left: 810px;
}
.completed-trials-section-dark .completed-trials-list .row5 .medium {
  width: 200px;
  align-items: center;
  justify-content: center;
  display: flex;
  min-width: 220px;
}
.completed-trials-section-dark .completed-trials-list .row5 img {
  width: 42px;
  margin-right: 18px;
}

.option-indicate .option-indicate-list span {
  width: 40px;
  height: 40px;
  min-width: 40px;
  border-radius: 11px;
  background: #e8e739;
}
.option-indicate .d-flex {
  gap: 58px;
}
.option-indicate .option-indicate-list span.gradient-indicate {
  background: linear-gradient(90deg, #9cc643, #159b80);
}
.option-indicate-list p {
  color: #fff;
  font-family: "Sofia Pro";
  font-weight: 900;
}
.option-indicate-list {
  display: flex;
  align-items: center;
  justify-content: center;
  gap: 28px;
}
.option-indicate {
  margin: 170px 0 0;
  padding-bottom: 52px;
}
.completed-trials-section-dark .completed-trials-note {
  margin-top: 34px;
  padding-bottom: 0px;
}
.planed-clinical-studies {
  padding: 85px 0 48px;
}
.planed-clinical-studies h2 {
  color: #159b80;
  padding: 0 40px;
  max-width: 1200px;
margin: 0 auto 32px;
  line-height: 95px;
  text-align: center;
}

.planed-clinical-studies h6 {
	text-align: center;
	color: #103f4e;
	padding: 0 40px;
	margin-bottom: 50px;
}
.planed-studies-boxes .planed-studies-box {
  border-radius: 17px;
  box-shadow: -9px -9px 22px #ffffff, 9px 2px 35px rgba(18, 61, 101, 25%);
  background: #edf5fc;
  text-align: center;
  flex-direction: column;
  display: flex;
  align-items: center;
  padding: 33px 18px;
  height: 100%;
}
.planed-studies-boxes .planed-studies-box .planed-studies-img {
  height: 200px;
  margin: 6px 0 13px;
}
.planed-studies-boxes .planed-studies-box img {
  height: 100%;
  max-width: 100%;
  object-fit: contain;
}
.planed-studies-boxes .planed-studies-box .play-btn img {
  max-width: 55px;
  width: 100%;
  margin: 0;
}
.planed-studies-boxes .planed-studies-box p {
  color: #3a5664;
  padding: 0 0 24px;
  margin: 0;
}
.planed-studies-boxes .planed-studies-box p span {
  color: #159b80;
}
.planed-studies-boxes {
  gap: 25px 0;
  justify-content: center;
}
.planed-clinical-studies p.indicate {
  font-size: 12px;
  color: #95a6bf;
  font-weight: 500;
  text-align: left;
  margin: 94px 0 0;
}

.f8-interaction-box.right {
  padding-left: 80px;
}

.investigator-study {
  padding: 129px 0;
}
.investigator-study h6 {
  color: #103f4e;
  text-align: center;
}
.investigator-study .motivate-img {
  max-width: 510px;
  margin: 27px auto 40px;
  border-radius: 16px;
}
.investigator-study .motivate-img:hover {
  background: linear-gradient(105.12deg, #e8f1f9 0%, #edf5fc 33.7%);
}
.motivate-study-section h6 {
  margin: 0 0 29px;
  color: #159b80;
  text-align: left;
}
.investigator-study {
  padding: 129px 0;
}
.objective p,
.objective ul li,
.coordinating p,
.more-details p {
  font-size: 22px;
  color: #3a5664;
  line-height: 30px;
  font-weight: 700;
  letter-spacing: 0.01px;
  font-family: "Raleway";
}
.objective ul {
  list-style-type: disc;
  padding: 0 0 0 33px;
  margin: 20px 0;
}
.objective ul li,
.coordinating p {
  margin: 0 0 16px;
}
.coordinating p {
  margin: 0 0 19px;
}
.more-details p {
  margin: 0 0 53px;
}
.more-details {
  margin: 47px 0 0;
}

.more-details a {
  border-radius: 17px;
  box-shadow: -9px -9px 22px #ffffff, 9px 2px 35px rgba(18, 61, 101, 25%);
  background: #edf5fc;
  display: flex;
  align-items: center;
  padding: 22px 33px 22px 22px;
  font-size: 22px;
  color: #159b80;
  font-weight: 700;
  letter-spacing: 0.01px;
  font-family: "Raleway";
  max-width: 577px;
  width: 100%;
  display: flex;
  align-items: center;
  gap: 19px;
  text-decoration: none;
  margin: 0 0 5px;
}
.more-details a img.external-link {
  margin-left: auto;
}
.more-details a img {
  width: 31px;
}
.motivate-study-section .completed-trials-note {
  margin-top: 32px;
  padding: 0;
}

sub {
  bottom: -0.25em;
  font-size: 50%;
}

.f8-interaction.dark {
  padding: 95px 0 205px;
  background: #103f4e;
}
.f8-interaction .heading h2,
.bone-joint h2 {
  color: #dbdb27;
  text-align: center;
  line-height: 69px;
}

.f8-interaction-content h6,
.f8-interaction .heading h6 {
  text-align: center;
  color: #fff;
  margin: 0 auto;
  line-height: 40px;
}
.f8-interaction .heading h6 {
  max-width: 1100px;
  margin: 30px auto 61px;
}
.f8-interaction-content h6 span {
  color: #dbd927;
}
.f8-interaction-content .f8-interaction-box {
  padding: 35px 27px;
  background: #103f4e;
  box-shadow: -9px -9px 22px #21596b, 9px 2px 35px rgba(2, 17, 31, 65%);
  border-radius: 17px;
  max-width: 617px;
  height: 100%;
  margin: 0 !important;
}
.f8-interaction-content h6 {
  margin: 0 auto 110px;
}
.f8-interaction-box-text p {
  margin: 0 0 10px;
  line-height: 30px;
  color: #ffffff;
  text-align: center;
}
.f8-interaction-box-text h6,
.f8-interaction-box h6,
.f8-interaction-box.right h6 {
  text-align: center;
  color: #dbd927;
  margin: 22px 0 28px;
}
.f8-interaction-box.right h6 {
  line-height: 40px;
  margin: 0 0 40px;
}
.f8-interaction-box.right img {
  margin: 0 auto;
}
.f8-interaction-box.right p {
  line-height: 30px;
  margin: 30px 0 0;
  color: #ffffff;
  text-align: center;
  padding: 0 20px;
}
.f8-interaction-box .d-flex h6 {
  color: #fff;
  margin: 0;
  text-align: left;
}
.f8-interaction-box-text {
  margin-top: 25px;
}
.function-factor-section .completed-trials {
  padding: 84px 0 0;
}
.function-factor-section .completed-trials h6,
.function-factor h6 {
  color: #fff;
}
.function-factor-section .completed-trials-content-img {
  text-align: center;
}

.function-factor-section .completed-trials-content-img img {
  margin: 0 auto;
  max-width: 330px;
}

.function-factor h6 {
  max-width: 1100px;
  width: 100%;
  text-align: center;
  margin: 40px auto 28px;
  line-height: 40px;
  font-weight: 500;
}
.function-factor-box {
  padding: 0 6%;
}

.function-factor .function-factor-box p {
  line-height: 30px;
  margin: 0;
  padding: 0 10px;
  color: #ffffff;
  font-weight: 500;
}

.function-factor .function-factor-box p span {
  color: #dbd927;
}
.function-factor-box img {
  margin: 0 0 32px;
}
.function-factor-section {
  padding: 125px 0 11px;
}
.function-factor {
  padding: 0 0 300px;
}
.function-factor-section .completed-trials-content {
  margin-top: 52px;
  padding-top: 20px;
}
.heading sub {
  font-weight: 500;
}

.bone-joint .heading h2 {
  color: #159b80;
  margin-bottom: 26px;
}
.bone-joint .heading h6,
.bone-joint-content .f8-interaction-box h6,
.arthropathy-section h6 {
  color: #103f4e;
  line-height: 40px;
}
.bone-joint-content {
  margin-top: 98px;
}
.bone-joint .heading p span {
  color: #159b80;
}

.bone-joint-content .f8-interaction-box h6 {
  margin: 0 0;
}
.bone-joint-content .bone-joint-box h6 {
  font-size: 22px;
  line-height: 30px;
}
.bone-joint-content .bone-joint-box img {
  max-width: 170px;
  margin: 0 auto 30px;
}
.bone-joint-content .bone-joint-box {
  width: 50%;
  margin: 0 auto;
  text-align: center;
  max-width: 240px;
}
.bone-joint-content .f8-interaction-box h6 {
  margin: 0 0 49px;
}
.bone-joint-content .bone-joint-box h6 span,
.bone-joint-content .f8-interaction-box h6 span,
.arthropathy-section h6 span {
  color: #159b80;
}
.bone-replace {
  background: #dfe9f3;
  box-shadow: -9px -9px 22px #ffffff, 9px 2px 35px rgba(18, 61, 101, 25%);
  border-radius: 17px;
  padding: 15px 16px;
}
.bone-replace .f8-interaction-box.right {
  padding-left: 80px;
}
.bone-replace img {
  max-width: 97px;
}
.page-inner .bone-replace p {
  margin-left: 20px;
  color: #3a5664;
  font-size: 22px;
  line-height: 30px;
}
.page-inner .joint-bleeding-flex p,
.page-inner .f8-prophylaxis p,
.page-inner .f8-platelets p {
  font-size: 22px;
  line-height: 30px;
}
.bone-replac .f8-interaction-box.right {
  padding-left: 60px;
}
.bone-joint {
  padding: 100px 0;
}
.arthropathy-section h6 {
  max-width: 1200px;
  margin: 0 auto;
}
.arthropathy-section {
  margin: 246px 0 100px;
}
.arthropathy-section-inner {
  margin: 132px 0 0;
}
.joint-bleeding .joint-bleeding-box {
  text-align: center;
}

.joint-bleeding .joint-bleeding-box img {
  max-width: 306px;
  width: 100%;
  margin: 0 auto 20px;
}

.joint-bleeding .joint-bleeding-box p {
  color: #159b80;
}
.joint-bleeding .bone-replace {
  max-width: 538px;
  margin: 0 auto;
}

.joint-bleeding .bone-replace {
  max-width: 538px;
  margin: 50px auto 0;
}
.joint-bleeding .bone-replace p {
  margin: 0;
}
.joint-bleeding.right img {
  max-width: 306px;
  width: 100%;
  margin: 28px auto;
}
.joint-bleeding-flex {
  max-width: 350px;
  margin: 0 auto;
}

.joint-bleeding-flex p,
.f8-prophylaxis p,
.f8-platelets p {
  color: #103f4e;
  line-height: 30px;
}

.joint-bleeding-flex p span,
.f8-prophylaxis-box p span {
  color: #159b80;
  font-family: "Sofia Pro";
}
.joint-bleeding-flex p {
  text-align: center;
}
.joint-bleeding-flex h2 {
  color: #159b80;
  font-weight: 600;
}
.f8-prophylaxis {
  margin: 0 auto;
}
.f8-prophylaxis-box p {
  padding: 0 8px;
  margin: 0 0 40px;
}
.f8-prophylaxis-box img {
  max-width: 418px;
  margin: 0 auto;
}
.f8-platelets-inner {
  max-width: 1330px;
  margin: 0 auto;
}
.f8-platelets h2 {
  color: #159b80;
  line-height: 90px;
  margin: 0 0 28px;
}
.f8-platelets-inner h6 {
  max-width: 1100px;
  margin: 0 auto;
  line-height: 40px;
  color: rgba(58, 86, 100, 1);
}
.platelets-describe .platelets-box {
  background: #e9f2fa;
  box-shadow: -9px -9px 22px #ffffff, 9px 2px 35px rgba(18, 61, 101, 25%);
  border-radius: 17px;
  padding: 21px 19px;
}
.platelets-left .platelets-box {
  text-align: right;
}
.platelets-center .platelets-box {
  text-align: center;
}

.platelets-left p,
.platelets-right p,
.platelets-center p {
  color: #3a5664;
}
.platelets-center img {
  max-width: 430px;
  z-index: 1;
  position: relative;
}
.platelets-describe {
  margin: 100px 0 0;
}
.platelets-describe .platelets-left,
.platelets-describe .platelets-right {
  margin: 70px 0 0;
}
.platelets-describe .platelets-left .first {
  right: -127px;
  max-width: 400px;
  position: relative;
}
.platelets-describe .platelets-right .first {
  margin-left: -45px;
  position: relative;
  left: -52px;
}
.platelets-describe .platelets-left .first,
.platelets-describe .platelets-right .first {
  margin-bottom: 64px;
}
.platelets-left p {
  text-align: right;
  color: #159b80;
  margin: 0 33px 22px 0;
}
.platelets-left .platelets-box p {
  margin: 0 0;
  color: #3a5664;
}
.platelets-left .platelets-box p span,
.bone-joint .heading h6 span {
  color: rgba(21, 155, 128, 1);
}
.platelets-left .platelets-box.second {
  margin-right: 28px;
}
.platelets-describe .platelets-right .platelets-box.second {
  margin: 0px 0 0 9px;
}

.platelets-center .platelets-box {
  position: relative;
  margin-left: -40px;
  margin-right: -40px;
  margin-top: 35px;
}
.f8-platelets {
  padding: 50px 0 150px;
}
.platelets-center .platelets-box:before {
  content: "";
  position: absolute;
  left: 0;
  right: 0;
  margin: 0 auto;
  top: -102px;
  background: url(../image/top-arrow-side.png) no-repeat;
  background-size: 160px;
  width: 160px;
  height: 100%;
}
.f8-interaction.dark .heading h2 sub {
  font-weight: 900;
  font-size: 30px;
  line-height: 95px;
  bottom: 5px;
}
#protectNow .modal-dialog,
#motivateModern .modal-dialog,
#nuDimensionPower .modal-dialog {
  max-width: 900px;
}
.f8-interaction-box.right .f8-interaction-box-inner-img {
  display: flex;
  gap: 45px;
  justify-content: center;
  max-width: 385px;
  margin: 0 auto;
  position: relative;
}
.f8-interaction-box img.f8-interaction-box-left-img {
  max-width: 170px;
  margin-right: 20px;
}
.f8-interaction-box.right .f8-interaction-box-inner-img img {
  max-width: 170px;
}
.f8-interaction-box.right .f8-interaction-box-inner-img img.rotate-svg-top {
  position: absolute;
  width: auto;
  left: 50%;
  transform: translateX(-50%);
}
.f8-interaction-box.right .f8-interaction-box-inner-img img.rotate-svg-bottom {
  position: absolute;
  width: auto;
  left: 50%;
  transform: translateX(-50%);
  bottom: 0;
}
.f8-interaction.dark .f8-interaction-box .d-flex img {
  max-width: 170px;
}

.custom-video-sec.f8-interaction.dark {
  padding: 60px 0;
  margin-top: 60px;
}
/*  */

section.pdf-viewer-info {
	padding: 7rem 0 0;
}

section.pdf-viewer-info iframe {
	max-height: 100% !important;
	width: 100%;
	height: 100vh;
}
/* media */

@media only screen and (max-width: 1600px) {
  .completed-trials-section-dark .completed-trials h2 {
    margin: 0 0 22px;
  }
  .function-factor-section .completed-trials {
    padding: 50px 0 0;
  }
  .arthropathy-section {
    margin: 166px 0 100px;
  }
  .arthropathy-section-inner {
    margin: 80px 0 0;
  }
  .f8-platelets {
    padding: 60px 0 100px;
  }
  .f8-interaction.dark {
   padding: 80px 0 80px;
  }

  .function-factor h6 {
    max-width: 1000px;
    margin: 15px auto 28px;
  }
  .function-factor {
    padding: 0 0 40px;
  }
  .bone-joint .heading h2 {
    margin-bottom: 14px;
  }
  .bone-joint-content {
    margin-top: 64px;
  }
  .bone-joint .heading h6,
  .bone-joint-content .f8-interaction-box h6,
  .arthropathy-section h6 {
    line-height: 30px;
  }
  .joint-bleeding .joint-bleeding-box img {
   max-width: 180px;
  }
  .joint-bleeding.right img {
   max-width: 180px;
  }
.f8-prophylaxis .f8-prophylaxis-box p {
	font-size: 16px;
	line-height: 23px;
	margin: 0 0 25px;
}
  .joint-bleeding .bone-replace {
    max-width: 485px;
  }
  .joint-bleeding-flex {
    max-width: 330px;
  }
  .page-inner .joint-bleeding-flex h2 {
    font-size: 73px;
  }
  .f8-prophylaxis-box p {
    padding: 0 55px;
    margin: 0 0 50px;
  }
  .platelets-describe {
    margin: 35px 0 0;
  }
  .f8-interaction .heading h6 {
    max-width: 1000px;
    margin: 20px auto 31px;
  }
  .f8-interaction-content h6,
  .f8-interaction .heading h6 {
    line-height: 30px;
  }
  .f8-interaction-content h6 {
    margin: 0 auto 60px;
    max-width: 1020px;
  }
  .f8-interaction-content .f8-interaction-box-text h6,
  .f8-interaction-content .f8-interaction-box h6,
  .f8-interaction-content .f8-interaction-box.right h6 {
    margin: 22px 0 28px;
  }
  .f8-interaction-box.right h6 {
    line-height: 30px;
  }
  .f8-interaction-content .f8-interaction-box {
    max-width: 570px;
  }
  .f8-interaction-content .f8-interaction-box.right {
    margin-left: auto;
  }
  .page-inner h2 {
    font-size: 50px;
    line-height: 60px;
  }
  .page-inner h6 {
    font-size: 20px;
    line-height: 28px;
  }
  .f8-interaction-content .f8-interaction-box {
	margin: auto !important;
}
  .page-inner p {
    font-size: 20px;
    line-height: 30px;
  }
  .completed-trials-section-dark .completed-trials-content {
    margin: 20px -8px 12px;
    padding: 0px 8px;
  }
  .function-factor-section .completed-trials-content-img img {
    max-width: 280px;
  }
  .function-factor-box {
    padding: 0 8%;
  }
  .arthropathy-section h6 {
    max-width: 1000px;
  }
  .f8-interaction-box .bone-replace .d-flex img {
    max-width: 110px;
    height: auto;
  }
  .nuwiq-trials-content {
    padding-right: 100px;
  }
  .completed-trials-content .flow-arrow {
    padding: 0 14px;
  }
  .completed-trials-content {
    padding: 0 18px;
    margin: 0 -18px 100px;
  }
  .completed-trials-note {
	margin-top: 50px;
	padding-bottom: 20px;
}
  .completed-trials-section-dark .completed-trials-list .row2 {
    margin-left: 20px;
  }
  .option-indicate {
		margin: 30px 0 0;
		padding-bottom: 22px;
  }
  section.explore-sec .explore-sec-inner .explore-sec-img img, .completed-trials-section-dark .completed-trials-list .row3 img, .completed-trials-section-dark .completed-trials-list .row4 img, .completed-trials-section-dark .completed-trials-list .row5 img {
	width: 33px;
}
  .planed-clinical-studies h2 {
    padding: 0 10px;
    max-width: 1200px;
    margin: 0 auto 17px;
  }
  .planed-clinical-studies {
    padding: 115px 0 48px;
  }
  .planed-clinical-studies h6 {
    margin-bottom: 150px;
  }
  .planed-studies-boxes {
    padding: 0 85px;
  }
  .investigator-study {
    padding: 50px 0;
  }
  .more-details a {
    font-size: 20px;
    max-width: 510px;
  }
  .f8-platelets-inner .platelets-box p {
	font-size: 18px;
	line-height: 25px;
}
.completed-trials-list {
	gap: 35px;
	display: flex;
	flex-direction: column;
	margin-top: 30px;
	row-gap: 25px;
} 

section.bone-joint .bone-joint-content {
	margin-top: 30px;
}

.bone-joint-content .f8-interaction-box h6 {
	margin: 0 0 25px;
	font-size: 16px;
	line-height: 22px;
}
.page-inner .bone-replace p {
	margin-left: 20px;
	font-size: 16px;
	line-height: 21px;
}
.bone-joint-content .bone-joint-box img {
	max-width: 140px;
	margin: 0 auto 15px;
}
.f8-interaction-content .f8-interaction-box-text h6, .f8-interaction-content .f8-interaction-box h6, .f8-interaction-content .f8-interaction-box.right h6 {
	margin: 10px 0 14px;
}
.page-inner h6 {
	font-size: 18px;
	line-height: 23px;
}

}

@media only screen and (max-width: 1540px) {
  .platelets-describe .platelets-left .first {
    right: -97px;
  }
  .nuwiq-trials .circle-one {
    width: 880px;
    height: 880px;
    top: -27%;
    left: -26%;
  }
  .planed-studies-boxes {
    padding: 0 20px;
  }
}
@media only screen and (max-width: 1439px) {
  .completed-trials-section-dark .completed-trials-content {
    padding: 0px 18px;
  }

  .function-factor h6 {
    max-width: 980px;
  }

  .arthropathy-section {
    margin: 136px 0 140px;
  }
  .bone-replace p {
    margin-left: 5px;
  }
  .bone-joint {
    padding: 100px 0 170px;
  }
  .f8-prophylaxis-box img {
    max-width: 398px;
  }
  .f8-prophylaxis-box p {
    padding: 0 45px;
    margin: 0 0 50px;
  }
  .nuwiq-trials-content {
    padding-top: 200px;
  }
  .completed-trials-content .year-btn {
    width: 70px;
    height: 70px;
    min-width: 70px;
    color: #159b80;
    font-size: 21px;
  }
  .planed-clinical-studies h6 {
    margin-bottom: 100px;
  }
  .completed-trials-content {
    padding: 0 8px;
    margin: 0 -8px 100px;
  }
  .planed-clinical-studies p.indicate {
    margin: 70px 0 0;
  }
}

@media only screen and (max-width: 1365px) {
  .function-factor-section .completed-trials {
    padding: 20px 0 0;
  }
  .function-factor-box {
    padding: 0 6%;
  }
  .f8-platelets-inner h6 {
    max-width: 900px;
  }
  .platelets-left .platelets-box.second {
    margin-right: 14px;
  }
  .f8-platelets p {
    font-size: 18px;
    line-height: 27px;
  }
  .f8-platelets {
    padding: 30px 0 120px;
  }
  .f8-interaction.dark {
    padding: 95px 0 125px;
  }
  .f8-interaction-content .f8-interaction-box {
    max-width: 580px;
  }
  .bone-joint {
    padding: 80px 0 120px;
  }
}
@media only screen and (max-width: 991px) {
  .f8-interaction-box.right {
    padding-left: 0;
  }
  .bone-replace {
    margin-bottom: 93px;
  }
  .joint-bleeding .bone-replace {
    margin-bottom: 93px;
  }
  .f8-prophylaxis-box img {
    max-width: 100%;
  }
  .custom-video-sec.f8-interaction.dark {
    padding: 30px 0;
    margin-top: 0;
  }
}
@media only screen and (max-width: 822px) {
  .completed-trials-list .gradient {
    font-size: 14px;
    line-height: 15px;
  }
  .page-inner h2 {
    font-size: 30px;
    line-height: 34px !important;
  }
  .more-details a {
    font-size: 14px;
  }
  .more-details a img {
    width: 21px;
  }
  .objective p,
  .objective ul li,
  .coordinating p,
  .more-details p {
    font-size: 16px;
    line-height: 26px;
  }
  .page-inner p {
    font-size: 16px;
    line-height: 31px;
  }
  .page-inner h6 {
    font-size: 18px;
    line-height: 22px;
  }
  .function-factor .function-factor-box p {
    line-height: 20px;
  }
  .function-factor-box {
    padding: 0 1%;
  }
  .f8-platelets p {
    font-size: 12px;
    line-height: 17px;
  }
  .platelets-center .platelets-box {
    margin-top: 25px;
  }
  .platelets-center .platelets-box:before {
    top: -76px;
  }
  .page-inner p {
    font-size: 16px;
    line-height: 20px;
  }
  .platelets-center img {
    max-width: 100%;
  }
}
@media only screen and (max-width: 767px) {
  .f8-interaction-content .f8-interaction-box.right {
    margin-left: 0;
  }
  .f8-interaction-content .f8-interaction-box {
    max-width: 100%;
  }
  .f8-interaction-content .col-sm-12.col-md-6 {
    margin-bottom: 30px;
  }
  .f8-prophylaxis-box img {
    max-width: 100%;
  }
  .function-factor-data {
    flex-wrap: wrap;
  }
}
@media only screen and (max-width: 575px) {
  .objective p,
  .objective ul li,
  .coordinating p,
  .more-details p {
    text-align: center;
  }
  .f8-interaction-box .f8-interaction-box-inner,
  .joint-bleeding-data {
    flex-wrap: wrap;
  }
  .bone-joint-content .bone-joint-box {
    width: 100%;
    max-width: 100%;
  }
}