@media screen and (min-width: 1902px) {
  .safety-info, section.nuprotect-study-sec.nuprotect-study-reduce {
    padding: 150px 0 60px;
  }

  .safety-info .quick-links-sec {
    padding-top: 50px;
  }

  .nuprotect-study-sec .nuprotect-study-content-second .nuprotect-study-bottom-desp {
    margin-top: 180px;
  }

  section.nuprotect-study-sec {
    padding: 40px 0 100px;
  }

  body section.pups-proven-effective-sec {
    padding: 50px 0px 180px;
  }

  .safety-info, section.nuprotect-study-sec.nuprotect-study-reduce {
    padding: 160px 0 220px;
  }

  .eight-check-analysis .heading {
    margin-bottom: 30px;
  }

  .eight-check-analysis .eight-check-analysis-content {
    padding: 40px 90px;
  }

  .eight-check-analysis .eight-check-analysis-inner {
    margin-bottom: 75px;
  }

  section.children-video-sec {
    padding: 70px 0 100px;
  }

  .children-video-sec .heading p, .efficacy-sec .heading p, .animate-sec-efficacy .heading p {
    font-size: 32px;
    line-height: 43px;
  }

  .safety-tolerability-sec .safety-tolerability-inner {
    padding: 80px 150px 52px;
  }

  body section.demonstrates-effrctive-sec, section.well-established-sec {
    padding: 130px 0;
  }

  body section.demonstrates-effrctive-sec, body section.well-established-sec {
    padding: 100px 0;
  }

  .eight-check-analysis .heading p, .safety-tolerability-sec .heading p, .well-established-sec .heading p, section.demonstrates-effrctive-sec .heading p {
    font-size: 40px;
    line-height: 49px;
  }

  .well-established-sec .heading h2, section.demonstrates-effrctive-sec .heading h2 {
    font-size: 67px;
    line-height: 69px;
    margin-bottom: 32px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next {
    padding-bottom: 60px;
  }

  section.prophylaxis-data-sec {
    padding: 130px 0 60px;
  }

  .produced-human-sec.flexible-dosing-section .produced-human-content {
    margin-top: 60px;
  }
}

@media screen and (max-width: 1900px) {
  section.banner-sec .banner-sec-inner {
    bottom: 20%;
    right: 11%;
  }

  section.banner-sec .banner-sec-inner p {
    font-size: 20px;
    max-width: 352px;
  }
}

@media screen and (max-width: 1699px) {
  .quick-links-sec .quick-links-data {
    margin-top: -245px;
  }

  .banner-tooltip .tooltip-data-1 {
    top: 23%;
    left: 17%;
  }

  .banner-tooltip .tooltip-data-2 {
    left: 24%;
    top: 34%;
  }

  .banner-tooltip .tooltip-data-3 {
    left: 25%;
    top: 42%;
  }

  .banner-tooltip .tooltip-data-6 {
    left: 66%;
    bottom: 41%;
  }
}

@media screen and (max-width: 1612px) {
  section.banner-sec .banner-sec-inner {
    bottom: 11%;
    right: 17%;
  }

}

@media screen and (max-width: 1600px) {

  header .navbar-nav li.menu-item {
    padding: 30px 0;
  }

  section.quick-links-sec {
    padding: 30px 0 0;
  }

  section.produced-human-sec.home-human-cells {
    padding-top: 60px;
  }

  .produced-human-sec .produced-human-data-first {
    margin-bottom: 300px;
  }

  section.explore-sec {
    padding: 50px 0 130px;
  }

  .group-slide-sec .page {
    min-height: 50vh;
  }

  section.text-with-img-sec {
    padding: 50px 0 240px;
  }

  section.video-sec {
    padding: 60px 0 60px;
  }

  section.video-sec .heading {
    margin-bottom: 50px;
  }

  .video-sec .video-sec-content {
    margin-bottom: 0;
  }

  section.pups-text-with-img-sec {
    padding-bottom: 140px;
  }

  section.produced-human-sec.adult-produced-human-sec {
    padding-top: 80px;
  }

  section.pups-text-with-img-sec.surgery-banner-sec,
  section.pups-text-with-img-sec.adult-banner-sec {
    padding-bottom: 80px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next {
    padding-bottom: 80px;
  }

  section.refernces-sec {
    padding: 70px 0;
  }

  section.demonstrates-effrctive-sec,
  section.well-established-sec {
    padding: 120px 0;
  }

  section.children-video-sec {
    padding: 80px 0;
  }

  section.safety-tolerability-sec {
    padding: 80px 0;
  }

  section.demonstrates-effrctive-sec {
    margin-top: 40px;
  }

  .produced-human-sec.flexible-dosing-section {
    padding: 70px 0 280px;
  }

  section.pups-text-with-img-sec.surgery-banner-sec.clinical-trials-banner-sec {
    padding-bottom: 120px;
  }

  .completed-trials-section-dark {
    padding: 80px 0 80px;
  }

  .bone-joint {
    padding: 80px 0 100px;
  }

  section.pups-text-with-img-sec {
    padding-top: 145px;
  }

  .text-with-img-sec p {
    font-size: 14px;
    line-height: 24px;
    margin: 12px 0;
  }

  .antigenic-epitopes-sec .antigenic-epitopes-right p {
    font-size: 16px;
    line-height: 22px;
  }

  .text-with-img-sec .text-with-img-list h4 {
    margin-bottom: 20px;
  }

  .text-with-img-sec .text-with-img-list li {
    padding: 16px 16px;
    font-size: 16px;
    line-height: 23px;
    margin-bottom: 14px;
  }

  .text-with-img-sec .text-with-img-list li span {
    font-size: 20px;
    line-height: 28px;
  }

  section.text-with-img-sec .text-with-img-content .text-with-img-content-left {
    align-self: flex-start;
    margin-top: 15px;
  }

  .video-sec .video-sec-content {
    margin-bottom: 0;
  }

  .text-with-img-sec h3 {
    font-size: 33px;
    line-height: 41px;
  }

  .text-with-img-sec h3 span {
    font-size: 30px;
    line-height: 38px;
  }

  section.refernces-sec {
    padding-bottom: 40px;
  }

  section.video-sec .heading h2 {
    margin-bottom: 20px;
  }

  section.explore-sec h3 {
    margin-bottom: 40px;
  }

  section.explore-sec .explore-sec-inner {
    row-gap: 20px;
  }

  section.explore-sec .explore-sec-inner .explore-sec-img img {
    width: 160px;
    height: 160px;
  }

  section.explore-sec h3 {
    font-size: 42px;
    line-height: 44px;
  }

  section.explore-sec .explore-sec-inner h4 {
    font-size: 18px;
    line-height: 22px;
    margin: 10px 0;
    min-height: 45px;
  }

  section.safety-info {
    padding-bottom: 70px;
  }

  section.produced-human-sec {
    padding-top: 50px;
  }

  section.eight-check-analysis {
    padding-top: 70px;
  }

  .eight-check-analysis .heading {
    margin-bottom: 20px;
  }

  .eight-check-analysis .eight-check-analysis-content {
    padding-top: 10px;
    padding-bottom: 40px;
  }

  .eight-check-analysis .eight-check-analysis-inner h4 {
    font-size: 30px;
    line-height: 30px;
  }

  .eight-check-analysis .eight-check-analysis-inner {
    margin-bottom: 50px;
  }

  .safety-info, section.nuprotect-study-sec.nuprotect-study-reduce {
    padding-top: 150px;
  }

  .eight-check-analysis .eight-check-analysis-inner .eight-check-analysis-list li {
    margin-bottom: 30px;
  }

  .pups-proven-effective-sec .heading h3 {
    margin-bottom: 20px;
  }

  section.pups-proven-effective-sec {
    padding-top: 50px;
    padding-bottom: 14rem;
  }


  section.demonstrates-effrctive-sec, section.well-established-sec {
    padding: 40px 0;
  }

  section.demonstrates-effrctive-sec .heading {
    margin-bottom: 20px;
  }

  .demonstrates-effrctive-sec .demonstrates-effrctive-inner, .well-established-sec .well-established-inner {
    padding: 20px 130px;
  }

  .demonstrates-effrctive-sec .demonstrates-effrctive-inner img {
    margin: 40px auto 20px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec .heading p, section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .heading p {
    font-size: 25px;
    line-height: 35px;
  }

  section.produced-human-sec.adult-produced-human-sec {
    padding-bottom: 280px;
  }

  body section.produced-human-sec.adult-produced-human-sec .heading {
    margin-bottom: 50px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec .heading h2, section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .heading h2 {
    font-size: 60px;
    line-height: 80px;
    margin-bottom: 4px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom h6 {
    margin: 0 auto 25px;
    font-size: 25px;
    line-height: 30px;
    max-width: 1200px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom {
    margin: 120px auto 0;
  }

  .produced-human-sec.flexible-dosing-section h2 {
    line-height: 70px;
    margin-bottom: 25px;
    font-size: 60px;
  }

  .produced-human-sec.flexible-dosing-section .produced-human-content {
    margin-top: 50px;
  }

  .prophylaxis-data-sec .heading h2, .vial-size-infusion-sec .heading h2 {
    font-size: 50px;
    line-height: 60px;
    margin-bottom: 10px;
  }

  .f8-interaction .f8-interaction-video {
    margin-bottom: 50px;
  }

  section.banner-sec {
    position: relative;
    padding: 75px 0;
  }

  .banner-tooltip .tooltip-data-1 {
    top: 20%;
    left: 17%;
  }

  .banner-tooltip .tooltip-data-2 {
    left: 24%;
    top: 32%;
  }

  .banner-tooltip .tooltip-data-3 {
    left: 25%;
    top: 41%;
  }

  .banner-tooltip .tooltip-data-5 {
    left: 55%;
    top: 36%;
    cursor: pointer;
  }

  .banner-tooltip .tooltip-data-4 {
    bottom: 25%;
    left: 19%;
  }

  .banner-tooltip .tooltip-data-6 {
    left: 66%;
    bottom: 39%;
  }

  section.nuprotect-study-sec {
    padding: 50px 0 128px;
  }

  .pups-proven-effective-sec .nuprotect-study-btn {
    margin-top: 0;
  }

  .children-video-sec .heading {
    margin-bottom: 30px;
  }

  .children-video-sec .heading p {
    font-size: 38px;
    line-height: 48px;
  }

  .video-btn {
    margin-top: 50px;
  }

  .safety-tolerability-sec .safety-tolerability-inner {
    padding: 40px 90px 40px;
    gap: 30px;
  }

  .children-video-sec .video-content {
    height: 580px;
  }

  .eight-check-analysis .heading p, .safety-tolerability-sec .heading p, .well-established-sec .heading p, section.demonstrates-effrctive-sec .heading p {
    font-size: 40px;
    line-height: 50px;
  }

  body section.produced-human-sec.adult-produced-human-sec {
    padding-bottom: 350px;
    padding-top: 160px;
  }

  .doosing-video-sec ul.video-list {
    margin-top: 40px;
  }

  body .prophylaxis-data-sec .heading {
    margin-bottom: 40px;
  }

  .planed-clinical-studies h6 {
    margin-bottom: 60px;
  }

  .planed-clinical-studies {
    padding: 70px 0 48px;
  }

  .planed-clinical-studies p.indicate {
    margin: 60px 0 0;
  }

  .quick-links-sec .quick-links-data {
    margin-top: -210px;
  }

  .banner-sec h1 {
    padding-top: 0;
    font-size: 60px;
    line-height: 60px;
  }

  body section.produced-human-sec.factor-human-sec {
    padding: 110px 0 270px;
  }

  body section.produced-human-sec.factor-human-sec .heading p {
    margin-bottom: 10px;
  }

  section.prophylaxis-data-sec {
    padding: 50px 0;
  }

  .vial-size-infusion-sec .heading p {
    font-size: 20px;
    line-height: 27px;
    max-width: 800px;
    margin-left: auto;
  }

  .vial-size-infusion-sec .heading h3 {
    font-size: 38px;
    line-height: 38px;
  }

  .produced-human-sec.pups-produced-human-sec .heading p {
    font-size: 30px;
    line-height: 38px;
  }

  .eight-check-analysis .bottom-data .bottom-data-text {
    padding: 16px 32px;
    font-size: 20px;
    line-height: 28px;
  }

  .children-video-sec .heading p, .efficacy-sec .heading p, .animate-sec-efficacy .heading p {
    font-size: 35px;
    line-height: 45px;
  }

  section.nuprotect-study-sec .heading h2 {
    font-size: 59px;
    line-height: 65px;
  }

  .nuprotect-study-graph-title {
    margin-bottom: 15px;
  }

  .nuprotect-study-sec .nuprotect-study-content .nuprotect-study-content-left p {
    font-size: 26px;
    line-height: 33px;
  }

  .nuprotect-study-svg #chart {
    width: 650px;
    height: 400px;
    position: relative;
  }

  .nuprotect-study-graph-title .custom-button {
    padding: 20px 20px;
    font-size: 16px;
    line-height: 23px;
  }

  .pups-proven-effective-sec .pups-proven-effective-content {
    margin-top: 60px;
  }

  .safety-tolerability-sec .heading h2 {
    font-size: 52px;
    line-height: 65px;
  }

  .safety-tolerability-sec .safety-tolerability-inner img {
    max-width: 240px;
    height: 240px;
  }

  .safety-tolerability-sec .safety-tolerability-inner p {
    font-size: 16px;
    line-height: 24px;
  }

  .well-established-sec .heading h2, section.demonstrates-effrctive-sec .heading h2 {
    font-size: 50px;
    line-height: 60px;
    margin-bottom: 15px;

  }

  .vial-size-infusion-sec .heading {
    margin-bottom: 20px;
  }

  .completed-trials-content .year-btn {
    width: 80px;
    height: 50px;
    min-width: 80px;
    ;
    font-size: 19px;
    line-height: normal;
  }
}

@media screen and (max-width: 1500px) {
  header nav.navbar img.image {
    width: 130px !important;
  }

  section.produced-human-sec {
    padding-top: 40px;
  }

  section.explore-sec .explore-sec-inner {
    row-gap: 40px;
  }

  section.explore-sec h3 {
    margin-bottom: 40px;
    font-size: 45px;
    line-height: 50px;
  }

  .text-with-img-sec p {
    font-size: 20px;
    line-height: 26px;
    letter-spacing: 0;
    margin: 20px 0;
  }

  .text-with-img-sec h3 {
    font-size: 45px;
    line-height: 50px;
  }

  section.video-sec .heading h2 {
    margin-bottom: 30px;
  }

  body section.produced-human-sec.adult-produced-human-sec {
    padding-bottom: 270px;
    padding-top: 130px;
  }

  body section.produced-human-sec.adult-produced-human-sec {
    padding-bottom: 200px;
    padding-top: 100px;
  }

}


@media screen and (max-width: 1440px) {
  .container {
    max-width: 1274px;
  }

  .text-with-img-content .text-with-img-content-left {
    max-width: 511px;
  }

  .children-video-sec .heading h2,
  .efficacy-animate-sec .slide-item-data.slide-item-datas h2,
  .efficacy-animate-sec .slide-item-datas h2,
  .efficacy-sec .heading h2,
  .eight-check-analysis .eight-check-analysis-center h2,
  .produced-human-sec.pups-produced-human-sec .heading h2,
  .prophylaxis-data-sec .heading h2,
  .pups-proven-effective-sec .heading h2,
  .pups-text-with-img-sec .pups-text-with-img-content h2,
  .safety-tolerability-sec .heading h2,
  .text-with-img-sec h2,
  .vial-size-infusion-sec .heading h2,
  .well-established-sec .heading h2,
  h1,
  section.demonstrates-effrctive-sec .heading h2,
  section.nuprotect-study-sec .heading h2,
  .animate-sec-efficacy .heading h2 {
    font-size: 50px;
    line-height: 60px;
  }

  section.banner-sec .banner-sec-inner {
    max-width: 526px;
    bottom: 12%;
    right: 18%;
  }

  section.banner-sec .banner-sec-inner h2 {
    font-size: 30px;
    line-height: 34px;
    letter-spacing: -0.36px;
    margin-bottom: 7px;
  }

  section.banner-sec .banner-sec-inner p {
    max-width: 370px;
    margin-bottom: 18px;
  }

  section.banner-sec .banner-sec-inner a.btn {
    font-size: 16px;
    line-height: 20px;
    padding: 9px 31px;
  }

  .quick-links-sec .quick-links-boxs h5,
  section.explore-sec .explore-sec-inner h4 {
    font-size: 18px;
    line-height: 20.21px;
  }

  .quick-links-sec .quick-links-boxs {
    padding: 20px;
  }

  .quick-links-icon img {
    width: 40px;
    height: 40px;
    min-width: 40px;
  }

  .text-with-img-sec h3 {
    font-size: 30px;
    line-height: 32.97px;
  }

  .text-with-img-sec h3 span {
    font-size: 24px;
    line-height: 32.97px;
  }

  section.text-with-img-sec .heading {
    max-width: 100%;
  }

  .text-with-img-sec p {
    font-size: 20px;
    margin: 35px 0;
  }

  .antigenic-epitopes-sec .antigenic-epitopes-right p,
  .nuprotect-study-sec .nuprotect-study-content .nuprotect-study-content-left p,
  .produced-human-sec .heading p,
  .produced-human-sec .produced-human-data-first .produced-human-content-left p,
  .prophylaxis-data-sec .prophylaxis-data-content .prophylaxis-data-content-right h3,
  .text-with-img-sec .text-with-img-list h4,
  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec .heading p,
  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .heading p,
  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom li,
  section.video-sec .heading p {
    font-size: 22px;
    line-height: 26px;
  }

  .text-with-img-sec .text-with-img-list li {
    font-size: 16px;
    line-height: 20.98px;
    letter-spacing: 0;
    margin-bottom: 11px;
    border-radius: 9px;
    padding: 12px 23px;
  }

  .text-with-img-sec .text-with-img-list li span {
    font-size: 20px;
    line-height: 25.17px;
  }

  section.produced-human-sec {
    padding: 50px 0 230px;
  }

  body .safety-info, section.nuprotect-study-sec.nuprotect-study-reduce {
    padding-top: 140px;
  }

  body section.nuprotect-study-sec.nuprotect-study-reduce {
    padding-bottom: 150px;
  }

  body section.eight-check-analysis {
    padding-top: 70px;
  }

  section.explore-sec h3 {
    font-size: 40px;
    line-height: 48px;
    margin-bottom: 80px;
  }

  section.explore-sec {
    padding: 40px 0 130px;
  }

  .group-slick-slider {
    padding: 302px 0;
  }

  .group-slick-slider .group-slider-inner,
  .group-slide-sec .details {
    max-width: 1070px;
  }

  .group-slick-slider .item h4 {
    font-size: 30px;
  }

  .group-slick-slider .item h2,
  .group-slide-sec .portofolio p {
    font-size: 40px;
  }

  .produced-human-sec .heading h2,
  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec .heading h2,
  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .heading h2 {
    font-size: 50px;
    letter-spacing: 0;
    margin-bottom: 10px;
    line-height: normal;
  }

  section.video-sec {
    padding: 54px 0 67px;
  }

  section.video-sec .heading h2 {
    font-size: 50px;
    margin-bottom: 25px;
    line-height: 60px;
  }

  section.video-sec .heading {
    margin-bottom: 62px;
  }

  .text-with-img-content {
    grid-template-columns: 1fr 1fr;
  }

  header .navbar-nav li.menu-item {
    padding: 28px 6px;
    margin: 0 15px;
  }

  .banner-tooltip .tooltip-box .tooltip-box-inner {
    width: 27px;
    height: 27px;
  }

  .banner-tooltip .tooltip-box {
    width: 56px;
    height: 56px;
  }

  .antigenic-epitopes-sec .antigenic-epitopes-rotate-img,
  .video-circle-layer .antigenic-epitopes-rotate-img {
    width: 240px;
    height: 240px;
  }

  .antigenic-epitopes-sec .antigenic-epitopes-circle-img,
  .video-circle-layer .antigenic-epitopes-circle-img {
    width: 340px;
    height: 340px;
  }

  img.antigenic-img-2.circle-image {
    bottom: -40px;
    left: -22px;
  }

  img.antigenic-img-1.circle-image {
    bottom: 74px;
    right: -86px;
  }

  .antigenic-epitopes-rotate-img .circle-one {
    top: -105%;
  }

  img.antigenic-img-3.circle-image {
    top: -45px;
    left: -16px;
  }

  .video-sec .video-sec-content {
    max-width: 820px;
    height: 472px;
  }

  .video-circle-layer {
    bottom: 0;
    left: 90px;
  }

  .circle-container .circle-image {
    width: 140px;
    height: 140px;
  }

  section.pups-text-with-img-sec {
    padding-top: 160px;
  }

  .pups-text-with-img-sec .pups-text-with-img-content h2 {
    font-size: 50px;
    line-height: 60px;
    margin-bottom: 30px;
  }

  .page-inner .f8-platelets p,
  .page-inner .f8-prophylaxis p,
  .page-inner .joint-bleeding-flex p,
  .pups-text-with-img-sec .pups-text-with-img-content p {
    font-size: 20px;
    line-height: 30px;
  }

  section.pups-proven-effective-sec {
    padding: 50px 0;
  }

  .prophylaxis-data-sec .heading p,
  .pups-proven-effective-sec .heading h3,
  .safety-tolerability-sec .heading p,
  .vial-size-infusion-sec .heading h3,
  .well-established-sec .heading p,
  section.demonstrates-effrctive-sec .heading p {
    font-size: 30px;
    line-height: 33px;
  }

  .efficacy-sec h4,
  .eight-check-analysis .eight-check-analysis-inner h4,
  .pups-proven-effective-sec .heading p,
  .pups-proven-effective-sec .pups-proven-effective-content p,
  .vial-size-infusion-sec .heading p {
    font-size: 22px;
    line-height: 30px;
  }

  .pups-proven-effective-sec .pups-proven-effective-content {
    gap: 21px;
  }

  section.nuprotect-study-sec {
    padding: 30px 0 80px;
  }

  section.nuprotect-study-sec .heading p {
    font-size: 30px;
    line-height: 33px;
    max-width: 758px;
  }

  section.nuprotect-study-sec.nuprotect-study-reduce {
    padding-top: 100px;
  }

  .nuprotect-study-sec .cstm-sub-desp {
    font-size: 22px;
    line-height: 30px;
    margin-bottom: 71px;
  }

  .produced-human-sec.pups-produced-human-sec .heading p {
    font-size: 30px;
    line-height: 32px;
    max-width: 645px;
  }

  .eight-check-analysis .bottom-data .bottom-data-text {
    font-size: 18px;
    line-height: 24px;
  }

  .refernces-sec .heading h4 {
    font-size: 30px;
    line-height: 34px;
  }

  .refernces-sec .refernces-inner li {
    font-size: 20px;
  }

  .children-video-sec .heading p,
  .efficacy-sec .heading p {
    font-size: 30px;
    line-height: 32px;
  }

  section.demonstrates-effrctive-sec,
  section.well-established-sec {
    padding: 85px 0;
  }

  .demonstrates-effrctive-sec .demonstrates-effrctive-inner h4 {
    padding: 18px 36px;
    font-size: 16px;
    line-height: 20px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom h6 {
    font-size: 22px;
    line-height: 30px;
    max-width: 737px;
  }

  .doosing-video-sec ul.video-list li {
    line-height: 30px;
  }

  .prophylaxis-data-sec .prophylaxis-data-content .prophylaxis-data-content-right ul li {
    font-size: 20px;
    line-height: 26px;
  }

  .prophylaxis-data-sec .prophylaxis-data-content .prophylaxis-data-content-right .model-available span {
    font-size: 24px;
  }

  .prophylaxis-data-sec .prophylaxis-data-content .prophylaxis-data-content-right .model-available {
    font-size: 18px;
    line-height: 27px;
  }

  .group-slide-sec .portofolio h1 {
    font-size: 30px;
    line-height: 40px;
    margin-bottom: 24px;
  }

  .banner-tooltip .tooltip-data {
    left: -112px;
    top: -71px;
  }

  .produced-human-sec .heading h2 sup {
    font-size: 29px;
    top: -20px;
  }

  .vial-size-infusion-sec .heading h2 sup {
    font-size: 30px;
    top: -18px;
  }

  section.video-sec .heading h2 sup {
    font-size: 26px;
    top: -20px;
  }

  .group-slide-sec .details sup {
    top: -11px;
    font-size: 21px;
  }

  section.pups-proven-effective-sec h2 sup {
    font-size: 28px;
    top: -22px;
  }

  section.nuprotect-study-sec .heading p sup {
    font-size: 22px;
    top: -10px;
  }

  .nuprotect-study-sec .nuprotect-study-content .nuprotect-study-content-left p sup {
    font-size: 19px;
    top: -5px;
  }

  .nuprotect-study-sec .nuprotect-study-content .nuprotect-study-content-left p sup:last-child {
    top: -8px;
    font-size: 13px;
  }

  .efficacy-sec .heading h2 sup,
  .well-established-sec .heading p sup {
    font-size: 22px;
    top: -18px;
  }

  .safety-tolerability-sec .heading h2 sup {
    font-size: 24px;
    top: -20px;
  }

  .safety-tolerability-sec .safety-tolerability-inner {
    gap: 65px;
  }

  section.demonstrates-effrctive-sec .heading h2 sup {
    font-size: 32px;
  }

  .well-established-sec .heading h2 sup {
    font-size: 24px;
    top: -19px;
  }

  .planed-clinical-studies .heading h2 sup {
    font-size: 23px;
    top: -22px;
  }

  .completed-trials .heading h2 sup {
    font-size: 24px;
    top: -24px;
  }

  section.banner-sec {
    padding: 80px 0;
  }

  section.banner-sec .container {
    top: 80px;
    height: calc(100% - 166px);
  }

  .text-with-img-sec .text-with-img-content-right .circle-box-animate {
    left: 84px;
  }

  .text-with-img-content-right img {
    height: 400px;
  }

  section.text-with-img-sec .circle-box-animate svg {
    width: 395px !important;
  }

  .text-with-img-sec .text-with-img-content-right .circle-three {
    width: 420px;
    height: 420px;
  }

  .text-with-img-sec .text-with-img-content-right .circle-two {
    width: 534px;
    height: 534px;
  }

  .text-with-img-content-right .circle-one {
    top: -36%;
    width: 749px;
    height: 749px;
    left: -104px;
  }

  .produced-human-sec .heading h2 {
    max-width: 950px;
  }

  .produced-human-sec .antigenic-epitopes-rotate-img .circle-three {
    width: 440px;
    height: 440px;
  }

  .produced-human-sec .antigenic-epitopes-rotate-img .circle-two {
    width: 577px;
    height: 577px;
  }

  .produced-human-sec .antigenic-epitopes-rotate-img .circle-one {
    top: -126%;
    width: 843px;
    height: 843px;
    left: -280px;
  }

  img.antigenic-img-1.circle-image.active {
    bottom: 80px;
    right: -125px;
  }

  img.antigenic-img-2.circle-image.active {
    bottom: -76px;
    left: -32px;
  }

  .antigenic-epitopes-sec {
    gap: 56px;
  }

  img.antigenic-img-3.circle-image.active {
    top: -54px;
    left: -31px;
  }

  section.produced-human-sec .produced-human-content-right .circle-three {
    width: 344px;
    height: 344px;
  }

  section.produced-human-sec .produced-human-content-right .circle-two {
    width: 450px;
    height: 450px;
  }

  section.produced-human-sec .produced-human-content-right .circle-one {
    top: -90px;
    width: 657px;
    height: 657px;
    left: -121px;
  }

  .produced-human-sec .produced-human-data-first {
    gap: 155px;
    margin-bottom: 250px;
  }

  section.produced-human-sec .produced-human-content-right img {
    height: 480px;
  }

  .pups-text-with-img-sec .pups-text-with-img-content {
    grid-template-columns: 654px 1fr;
  }

  .circle-box-animate {
    position: absolute;
    top: 7px;
    left: -19px;
  }

  .pups-text-with-img-sec .circle-three {
    width: 744px;
    height: 744px;
  }

  .pups-text-with-img-sec .circle-two {
    width: 930px;
    height: 930px;
  }

  .pups-text-with-img-sec .circle-one {
    top: -327px;
    left: -362px !important;
    width: 1240px;
    height: 1240px;
  }

  .nuprotect-study-sec .nuprotect-study-content-second .nuprotect-study-bottom-desp {
    margin-top: 150px;
  }

  .pups-proven-effective-sec .pups-proven-effective-img-left .circle-one {
    left: 49px;
  }

  .nuprotect-study-sec .nuprotect-study-content-inner.nuprotect-study-content-third .circle-one {
    top: -38%;
    left: -91px;
  }

  .adult-banner-sec .circle-box-animate {
    top: 33px;
    left: 74px;
  }

  .adult-banner-sec .zoom-animate-circle {
    left: 23px;
    top: -39px;
  }

  .surgery-banner-sec .circle-box-animate {
    top: 21px;
    left: 62px;
  }

  .surgery-banner-sec .zoom-animate-circle {
    left: 7px;
    top: -55px;
  }

  .dosing-banner-sec .circle-box-animate {
    top: 12px;
    left: 32px;
  }

  .dosing-banner-sec .zoom-animate-circle {
    left: 0;
    top: -37px;
  }

  .pups-text-with-img-sec.childern-banner-sec .circle-box-animate {
    top: 10px;
    left: 61px;
  }

  .pups-text-with-img-sec.childern-banner-sec .zoom-animate-circle {
    left: 21px;
    top: -49px;
  }

  .flexible-dosing-section.produced-human-sec .produced-human-content-right .circle-one {
    top: -134px;
    left: -45px;
  }

  .f8-prophylaxis-grpah-chart .x-axis-higher-data {
    right: 10px;
  }

  .text-with-img-sec .text-with-img-content-right .circle-box-animate-text svg {
    width: 320px;
  }

  #cstm-text-with-img-sec .circle-box-animate-text {
    top: 16px;
    left: 58px;
  }

  .text-with-img-sec .text-with-img-content-right .zoom-animate-circle {
    left: 24px;
    top: -23px;
  }

  .clinical-trials-banner-sec .circle-box-animate {
    top: 6px;
    left: 64px;
  }

  .clinical-trials-banner-sec .zoom-animate-circle {
    left: 7px;
    top: -67px;
  }

  .pups-text-with-img-sec .circle-box-animate {
    top: 9px;
    left: 51px;
  }

  .pups-text-with-img-sec .zoom-animate-circle {
    left: -6px;
    top: -58px;
  }

  .quick-links-sec .quick-links-data {
    margin-top: -176px;
  }

  .quick-download-link img {
    height: auto;
    width: 21px;
  }

  .banner-tooltip .tooltip-data-1 {
    top: 24%;
    left: 16%;
  }

  .banner-tooltip .tooltip-data-2 {
    left: 22.7%;
    top: 34.7%;
  }

  .banner-tooltip .tooltip-data-3 {
    left: 24%;
    top: 42.3%;
  }

  .text-with-img-sec h2 span {
    font-weight: 400;
    font-size: 24px;
    line-height: 32.97px;
    letter-spacing: 0;
  }

  section.explore-sec .explore-sec-inner .explore-sec-img img {
    width: 218px;
    height: 218px;
  }

  section.text-with-img-sec {
    padding: 50px 0 180px;
  }

  .group-slide-sec .page {
    min-height: 40vh;
  }

  section.explore-sec .download-icon img {
    width: 26px;
    height: auto;
  }

  section.refernces-sec {
    padding: 84px 0;
  }

  .refernces-sec .refernces-inner {
    max-width: 1050px;
    margin: 0 auto;
  }

  .produced-human-sec .produced-cell-video {
    left: calc(50% - 14%);
  }

  .text-with-img-sec .text-with-img-content-right {
    margin-right: 20%;
  }

  @keyframes zoomIn {
    0% {
      transform: scale(0.2);
      opacity: 0;
    }

    100% {
      transform: scale(1.7);
      opacity: 1;
    }
  }

  @keyframes zoomInrotate {
    0% {
      transform: scale(0.2);
      opacity: 0;
    }

    100% {
      transform: scale(3);
      opacity: 1;
    }
  }

  .home-human-cells .produced-cells-data {
    padding-left: 6%;
  }

  .produced-human-sec.home-human-cells ul li:last-child {
    max-width: 366px;
    flex: 0 0 366px;
  }

  .pups-produced-human-next.pups-produced-human-right-rotate img.antigenic-img-1.circle-image.active {
    bottom: 80px;
    right: 202px;
  }

  .pups-produced-human-next.pups-produced-human-right-rotate img.antigenic-img-3.circle-image {
    top: 200px;
    right: -43px;
    left: auto;
  }

  .pups-produced-human-next.pups-produced-human-right-rotate img.antigenic-img-2.circle-image.active {
    bottom: 214px;
    right: -30px;
    left: auto;
  }

  .pups-produced-human-next.pups-produced-human-right-rotate img.antigenic-img-3.circle-image.active {
    top: 217px;
    right: -20px;
    left: auto;
  }

  .pups-produced-human-next.pups-produced-human-right-rotate img.antigenic-img-1.circle-image {
    bottom: 110px;
    right: 192px;
  }

  #home-human-cells .antigenic-epitopes-sec .zoom-animate-circle {
    left: -18px;
    top: -14px;
  }

  #pups-proven-effective-sec .pups-proven-effective-img-left .zoom-animate-circle {
    top: -59%;
    right: -26%;
  }

  .f8-prophylaxis-grpah-chart.chart-container {
    margin-left: 60px;
  }

  #cstm-nuprotect-study-sec .nuprotect-study-content-right .zoom-animate-circle {
    left: -29px;
    top: -25%;
  }

  .antigenic-epitopes-rotate-img .zoom-animate-circle {
    left: 0;
    top: -2px;
  }

  .f8-interaction-box-graph .graph-info ul li,
  .f8-interaction-box-graph svg text,
  .f8-prophylaxis-grpah-chart .y-axis-label,
  .nuprotect-study-svg svg text {
    font-size: 16px;
  }

  .f8-prophylaxis-grpah-chart .bar .label {
    font-size: 16px;
    line-height: 21px;
  }

  .f8-prophylaxis-grpah-chart .bar {
    width: 53px;
  }

  .f8-prophylaxis-grpah-chart.pupschart .y-axis-label:after {
    width: 569px;
  }

  .eight-check-analysis .eight-check-analysis-inner .eight-check-analysis-list li p br {
    display: none;
  }

  .efficacy-animate-sec .slide-item-data.slide-item-datas h5,
  .efficacy-animate-sec .slide-item-datas h5,
  .custom-content-box h4 {
    font-size: 22px;
    margin-top: 14px;
  }

  .efficacy-animate-sec .slide-data-grid {
    gap: 70px;
  }

  .efficacy-animate-sec .slide-data-grid .slide-data-grid-right ul li .list-count {
    font-size: 50px;
    width: 104px;
    height: 104px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom li a {
    font-size: 22px;
    line-height: 34px;
    padding: 10px 20px;
  }

  #flexible-dosing-section .produced-human-content-right .zoom-animate-circle {
    top: -28%;
  }

  .pups-text-with-img-sec.dosing-banner-sec .zoom-animate-circle {
    left: 24px;
    top: -38px;
  }

  .falling-item {
    height: 150px;
    width: 40px;
  }

  .falling-item-inner {
    gap: 25px;
    justify-content: center;
  }

  .f8-prophylaxis-box p {
    min-height: 121px;
  }

  .f8-prophylaxis-grpah-chart .x-axis-higher-data .x-axis {
    font-size: 16px;
    line-height: 20px;
  }

  .f8-prophylaxis-grpah-chart .y-axis {
    left: -50px;
    font-size: 16px;
  }

  .f8-prophylaxis-grpah-chart .y-axis-labels .y-axis-label:last-child:after {
    top: 15px;
  }

  .f8-prophylaxis-grpah-chart .bar:before {
    left: -37px;
    bottom: -10px;
  }

  .f8-prophylaxis-grpah-chart .y-axis-label:after {
    width: 250px;
  }

  .f8-prophylaxis-grpah-chart-two .y-axis-label:after {
    left: 59px;
  }

  .f8-interaction-box-graph .graph-years-title {
    left: -20px;
  }

  .f8-interaction-box-graph .graph-age-title {
    font-size: 16px;
    line-height: 23px;
  }

  .falling-wrapper {
    max-width: max-content;
    gap: 100px;
    margin: 0 auto;
  }

  .f8-prophylaxis-grpah-chart .grpah-chart-value {
    left: 60px;
    font-size: 16px;
  }

  .f8-prophylaxis-grpah-chart-two .label-top {
    font-size: 16px;
    margin-bottom: 1px;
  }

  .safety-info {
    padding: 140px 0;
  }

  .f8-prophylaxis-grpah-chart .blue-bar {
    height: 327px;
  }

  @keyframes growBar {
    from {
      height: 0;
    }

    to {
      height: 142px;
    }
  }

  @keyframes growBartwo {
    from {
      height: 0;
    }

    to {
      height: 245px;
    }
  }

  .animate-sec-efficacy .right .slide {
    padding-bottom: 28%;
  }

  .animate-sec-efficacy .navigation {
    margin-top: -30%;
  }

  body section.produced-human-sec.factor-human-sec {
    padding: 190px 0 190px;
  }

  .arthropathy-section {
    margin: 90px 0 90px;
  }

  .antigenic-epitopes-sec .foot-note {
    bottom: -8%;
  }

  #post-1212 .entry-content {
    padding: 120px 40px;
  }

  .page-content.privacy-page {
    padding: 120px 0;
  }

  #post-1212 h1,
  .privacy-page h1 {
    font-size: 76px;
  }

  .pups-produced-human-sec .pups-produced-human-next {
    margin-top: 350px;
  }

  section.produced-human-sec.home-human-cells {
    padding-top: 40px;
  }

  body section.produced-human-sec.adult-produced-human-sec {
    padding-bottom: 240px;
    padding-top: 100px;
  }

  .produced-human-sec.flexible-dosing-section {
    padding: 80px 0 130px;
  }

  section.vial-size-infusion-sec {
    padding: 50px 0;
  }
}

@media screen and (max-width: 1280px) {
  .produced-human-sec .produced-cell-video {
    left: calc(50% - 11%);
  }

  #pupschart .blinking-zero,
  #pupschart.f8-prophylaxis-grpah-chart.pupschart .graph-info ul li,
  #pupschart.f8-prophylaxis-grpah-chart.pupschart .label-top,
  .produced-human-sec .produced-cells .produced-cell-data h6,
  .right-content-title h2 {
    font-size: 16px;
  }

  .banner-tooltip .tooltip-data-1 {
    top: 23%;
    left: 20%;
  }

  .banner-tooltip .tooltip-data-2 {
    left: 25.7%;
    top: 34%;
  }

  .banner-tooltip .tooltip-data-3 {
    left: 27%;
    top: 42%;
  }

  .banner-tooltip .tooltip-data-4 {
    bottom: 25%;
    left: 28%;
  }

  .banner-tooltip .tooltip-data-5 {
    left: 54%;
    top: 37%;
  }

  .banner-tooltip .tooltip-data-6 {
    left: 64%;
    bottom: 41%;
  }

  .banner-sec h1 {
    padding-top: 15px;
  }

  #pups-proven-effective-sec .pups-proven-effective-img-left .zoom-animate-circle {
    top: -57%;
  }

  .nuprotect-study-svg #chart {
    width: 620px;
    height: 410px;
  }

  .all-inhibitors {
    font-size: 16px;
    line-height: 20px;
    top: 42px;
  }

  .f8-prophylaxis-grpah-chart.pupschart .y-axis-label:after {
    width: 570px;
    left: 57px;
  }

  #pupschart.f8-prophylaxis-grpah-chart.pupschart .blue-bar.thirty-one {
    height: 197px;
  }

  #pupschart.f8-prophylaxis-grpah-chart.pupschart .blue-bar.forty-seven {
    height: 285px;
  }

  #pupschart #yellow-bar-graph-three {
    height: 264px;
  }

  @keyframes growBarthree {
    from {
      height: 0;
    }

    to {
      height: 197px;
    }
  }

  #pupschart.f8-prophylaxis-grpah-chart.pupschart .label-top {
    width: 40px;
    height: 40px;
  }

  .f8-prophylaxis-grpah-chart .bar .label img {
    width: 100px;
    margin: 0 auto;
  }

  .nuprotect-study-content-right .bottom-exposure-day {
    font-size: 16px;
    line-height: 21px;
  }

  .nuprotect-study-sec .nuprotect-study-content .nuprotect-study-content-left img {
    max-width: 245px;
  }

  .demonstrates-effrctive-sec .demonstrates-effrctive-inner img,
  .safety-tolerability-sec .safety-tolerability-inner img,
  .well-established-sec .well-established-inner .well-established-data img {
    max-width: 245px;
    height: 245px;
  }

  .animate-sec-efficacy .right .slide {
    padding-bottom: 17%;
  }

  .animate-sec-efficacy .navigation {
    margin-top: -18%;
  }

  .f8-prophylaxis-grpah-chart .bar .label {
    left: -17px;
    min-width: 146px;
  }

  .f8-prophylaxis-grpah-chart.pupschart .label-axis-number {
    left: 14px;
  }
}

@media screen and (max-width: 1180px) {
  section.explore-sec h3 {
    font-size: 32px;
    line-height: 45px;
    margin-bottom: 45px;
  }

  .group-slide-sec .page {
    min-height: 30vh;
  }
}

@media screen and (max-width: 1024px) {
  section.banner-sec {
    min-height: 700px;
    background-size: cover;
  }

  section.explore-sec .explore-sec-inner {
    gap: 25px;
  }

  section.explore-sec .explore-sec-inner .explore-sec-img img {
    max-width: 218px;
    width: 218px;
    height: 218px;
  }

  .produced-human-sec .produced-human-data-first,
  .prophylaxis-data-sec .prophylaxis-data-content {
    gap: 15px;
  }

  .efficacy-animate-sec .slide-data-grid,
  .produced-human-sec.home-human-cells .antigenic-epitopes-sec {
    gap: 50px;
    grid-template-columns: 1fr 1fr;
  }

  .banner-tooltip .tooltip-data-1 {
    top: 24%;
  }

  .banner-tooltip .tooltip-data-2 {
    left: 26%;
    top: 35%;
  }

  .banner-tooltip .tooltip-box {
    width: 36px;
    height: 36px;
  }

  .banner-tooltip .tooltip-box .tooltip-box-inner {
    width: 20px;
    height: 20px;
  }

  .banner-tooltip .tooltip-data-3 {
    left: 28%;
    top: 42.5%;
  }

  .banner-tooltip .tooltip-data-4 {
    bottom: 29%;
    left: 23%;
  }

  .banner-tooltip .tooltip-data-5 {
    left: 54%;
    top: 39%;
  }

  .banner-tooltip .tooltip-data-6 {
    left: 64%;
    bottom: 43%;
  }

  .banner-tooltip .tooltip-data {
    left: -122px;
    top: -83px;
  }

  section.banner-sec .banner-sec-inner {
    right: 14%;
    bottom: 13%;
  }

  header .navbar-nav li.menu-item {
    margin: 0 8px;
  }

  header .navbar-nav li.menu-item a.nav-link {
    font-size: 14px;
  }

  .efficacy-animate-sec .slide-item-data.slide-item-datas h2,
  .efficacy-animate-sec .slide-item-datas h2,
  .efficacy-sec .heading h2,
  .produced-human-sec.pups-produced-human-sec .heading h2,
  .prophylaxis-data-sec .heading h2,
  .pups-proven-effective-sec .heading h2,
  .pups-text-with-img-sec .pups-text-with-img-content h2,
  .safety-tolerability-sec .heading h2,
  .vial-size-infusion-sec .heading h2,
  .well-established-sec .heading h2,
  section.demonstrates-effrctive-sec .heading h2,
  section.nuprotect-study-sec .heading h2,
  .animate-sec-efficacy .heading h2 {
    font-size: 40px;
    line-height: 50px;
  }

  .pups-proven-effective-sec .heading p,
  .pups-text-with-img-sec .pups-text-with-img-content p {
    font-size: 18px;
    line-height: 26px;
  }

  .pups-text-with-img-sec .circle-one {
    top: -268px;
    left: -274px;
  }

  .pups-proven-effective-sec .heading h3 {
    margin-bottom: 40px;
  }

  .pups-proven-effective-sec .pups-proven-effective-content p {
    font-size: 20px;
    line-height: 28px;
  }

  .pups-proven-effective-sec .pups-proven-effective-img-left .circle-one {
    top: -76%;
    left: -320px;
  }

  section.nuprotect-study-sec {
    padding: 84px 0;
  }

  section.nuprotect-study-sec .heading p {
    font-size: 28px;
    line-height: 32px;
  }

  section.eight-check-analysis {
    padding: 84px 0 45px;
  }

  .eight-check-analysis .heading h2 {
    font-size: 52px;
    line-height: 75px;
  }

  .eight-check-analysis .heading p {
    font-size: 32px;
    line-height: 44px;
  }

  .eight-check-analysis .eight-check-analysis-inner,
  .nuprotect-study-sec .nuprotect-study-content {
    grid-template-columns: 1fr;
  }

  .eight-check-analysis .eight-check-analysis-left {
    order: 2;
  }

  .eight-check-analysis .eight-check-analysis-center {
    order: 1;
  }

  .eight-check-analysis .eight-check-analysis-inner .eight-check-analysis-right {
    order: 3;
  }

  .efficacy-sec .heading p,
  .prophylaxis-data-sec .heading p {
    font-size: 26px;
    line-height: 28px;
  }

  .demonstrates-effrctive-sec .demonstrates-effrctive-inner p,
  .efficacy-sec h4 {
    font-size: 20px;
    line-height: 26px;
  }

  .efficacy-animate-sec .slide-item-data.slide-item-datas h3,
  .efficacy-animate-sec .slide-item-datas h3,
  .safety-tolerability-sec .heading p,
  .well-established-sec .heading p,
  section.demonstrates-effrctive-sec .heading p,
  .animate-sec-efficacy .heading p {
    font-size: 24px;
    line-height: 26px;
  }

  .safety-tolerability-sec .safety-tolerability-inner p,
  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom li {
    font-size: 18px;
    line-height: 24px;
  }

  .safety-tolerability-sec .safety-tolerability-inner {
    gap: 50px;
    padding: 40px 20px 100px;
  }

  section.demonstrates-effrctive-sec {
    padding: 68px 0;
  }

  .demonstrates-effrctive-sec .demonstrates-effrctive-inner,
  .well-established-sec .well-established-inner {
    padding: 80px 40px;
  }

  .demonstrates-effrctive-sec .demonstrates-effrctive-inner h4 {
    font-size: 14px;
    line-height: 18px;
  }

  section.well-established-sec {
    padding: 65px 0;
  }

  .well-established-sec .well-established-inner .well-established-data p {
    font-size: 18px;
    line-height: 20px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom h6 {
    font-size: 20px;
    line-height: 24px;
  }

  .vial-size-infusion-sec .heading h3 {
    font-size: 26px;
    line-height: 30px;
  }

  .doosing-video-data ul.video-list {
    padding: 0 30px;
  }

  .prophylaxis-data-sec .prophylaxis-data-content .prophylaxis-data-content-right .model-available h6 {
    gap: 0;
  }

  .group-slide-sec .details {
    max-width: 720px;
  }

  .group-slide-sec .portofolio p {
    font-size: 32px;
  }

  .efficacy-animate-sec .navigation,
  .group-slide-sec .pages {
    right: 5%;
  }

  .antigenic-epitopes-sec {
    gap: 56px;
  }

  .text-with-img-sec h2 sup {
    top: -18px;
    font-size: 30px;
  }

  section.pups-proven-effective-sec h2 sup {
    font-size: 20px;
    top: -13px;
  }

  section.demonstrates-effrctive-sec .heading h2 sup {
    font-size: 26px;
  }

  section.banner-sec .banner-sec-inner p {
    font-size: 17px;
    line-height: 25px;
  }

  .banner-sec h1 {
    padding-top: 6px;
  }

  section.quick-links-sec {
    padding: 30px 0 0;
  }

  section.text-with-img-sec {
    padding: 70px 0 240px;
  }

  .text-with-img-sec .text-with-img-content-right {
    margin-right: 0;
  }

  .circle-container .circle-image {
    width: 110px;
    height: 110px;
  }

  .circle-container .circle-image.active {
    scale: 1.6;
  }

  .circle-container {
    width: 240px;
    height: 240px;
  }

  .antigenic-epitopes-sec .antigenic-epitopes-circle-img,
  .video-circle-layer .antigenic-epitopes-circle-img {
    width: 300px;
    height: 300px;
  }

  .antigenic-epitopes-sec .antigenic-epitopes-rotate-img,
  .video-circle-layer .antigenic-epitopes-rotate-img {
    width: 180px;
    height: 180px;
  }

  img.antigenic-img-1.circle-image.active {
    bottom: 72px;
    right: -93px;
  }

  img.antigenic-img-2.circle-image.active {
    bottom: -32px;
    left: -28px;
  }

  .pups-produced-human-next.pups-produced-human-right-rotate img.antigenic-img-1.circle-image {
    bottom: 90px;
    right: 152px;
  }

  .pups-produced-human-next.pups-produced-human-right-rotate img.antigenic-img-2.circle-image.active {
    bottom: 174px;
    right: -36px;
    left: auto;
  }

  .pups-produced-human-next.pups-produced-human-right-rotate img.antigenic-img-2.circle-image {
    bottom: 175px;
    right: -13px;
    left: auto;
  }

  .pups-produced-human-next.pups-produced-human-right-rotate img.antigenic-img-3.circle-image.active {
    top: 180px;
    right: -20px;
    left: auto;
  }

  .pups-produced-human-next.pups-produced-human-right-rotate img.antigenic-img-1.circle-image.active {
    bottom: 70px;
    right: 164px;
  }

  img.antigenic-img-3.circle-image.active {
    top: -44px;
    left: -33px;
  }

  #home-human-cells .antigenic-epitopes-sec .zoom-animate-circle {
    left: auto;
    top: -20px;
    right: -44px;
  }

  .produced-human-sec .antigenic-epitopes-sec .antigenic-epitopes-left {
    margin-left: 22%;
  }

  .produced-human-sec.home-human-cells ul li:last-child {
    max-width: 236px;
    flex: 0 0 236px;
  }

  .produced-human-sec .produced-cell-video svg {
    width: 30px;
  }

  .produced-human-sec .produced-cells .produced-cell-data h6 {
    font-size: 13px;
    line-height: 18px;
  }

  .produced-human-sec ul li img {
    min-width: 50px;
    object-fit: contain;
    width: 50px;
    height: 50px;
  }

  .produced-human-sec ul li {
    padding: 17px 12px;
    gap: 10px;
  }

  .produced-human-sec .produced-cell-video {
    max-width: -70px;
  }

  .refernces-sec .refernces-inner {
    max-width: 830px;
  }

  #cstm-nuprotect-study-sec .nuprotect-study-content,
  .pups-text-with-img-sec .pups-text-with-img-content {
    grid-template-columns: 1fr 1fr;
  }

  .nuprotect-study-sec .nuprotect-study-content-inner.nuprotect-study-content-second .nuprotect-study-content .nuprotect-study-content-left {
    margin-top: 160px;
  }

  #cstm-nuprotect-study-sec .nuprotect-study-content-right .zoom-animate-circle {
    top: -10%;
  }

  .pups-text-with-img-sec .zoom-animate-circle {
    left: 37px;
    top: -16px;
  }

  .pups-text-with-img-sec .zoom-animate-circle .zoom-animation {
    height: auto;
  }

  .nuprotect-study-wrapper {
    justify-content: center;
  }

  .f8-prophylaxis-grpah-chart.chart-container {
    margin-left: 0;
    justify-content: center;
  }

  .f8-prophylaxis-grpah-chart.pupschart .graph-info {
    top: 65px;
    left: 220px;
  }

  .f8-prophylaxis-grpah-chart .x-axis-higher-data {
    right: 0;
  }

  .f8-prophylaxis-grpah-chart .x-axis-higher-data .x-axis {
    max-width: 114px;
  }

  .f8-prophylaxis-grpah-chart .x-axis-higher-data .x-axis-higher-icon {
    width: 100px;
    height: 100px;
  }

  .nuprotect-study-sec .nuprotect-study-content-inner.nuprotect-study-content-third .nuprotect-study-content-left p br {
    display: none;
  }

  .pups-text-with-img-sec.childern-banner-sec .zoom-animate-circle {
    left: 63px;
    top: 1px;
  }

  .dosing-banner-sec .circle-box-animate svg,
  .pups-text-with-img-sec.childern-banner-sec .circle-box-animate svg {
    width: 370px;
  }

  .efficacy-animate-sec .slide-data-grid .slide-data-grid-right ul li .list-count {
    font-size: 40px;
    width: 94px;
    height: 94px;
  }

  @keyframes zoomIn {
    0% {
      transform: scale(0.2);
      opacity: 0;
    }

    100% {
      transform: scale(2);
      opacity: 1;
    }
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom li a {
    font-size: 18px;
    line-height: 24px;
    padding: 8px 20px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom li span img {
    width: 65px;
    height: 65px;
    min-width: 65px;
  }

  .pups-produced-human-next.pups-produced-human-right-rotate img.antigenic-img-3.circle-image {
    top: 170px;
    right: -33px;
  }

  #flexible-dosing-section .produced-human-content-right .zoom-animate-circle {
    top: -12%;
  }

  .doosing-video-sec ul.video-list {
    padding-left: 50px;
  }

  .planed-studies-boxes .planed-studies-box p {
    font-size: 16px;
    line-height: 24px;
  }

  .right-content-title {
    left: 190px;
  }

  .platelets-center .platelets-center-inner img {
    max-width: 120px;
  }

  .f8-platelets p {
    font-size: 12px;
    line-height: 20px;
  }

  .platelets-describe .platelets-left .first {
    right: -38px;
  }

  .platelets-describe .platelets-left .first,
  .platelets-describe .platelets-right .first {
    margin-bottom: 16px;
  }

  .platelets-describe .platelets-right .first {
    left: -38px;
  }

  .platelets-center .platelets-center-inner .platelets-center-third-arrow {
    left: 40.6%;
  }

  .platelets-center .platelets-box:before {
    top: -81px;
  }

  .f8-interaction-box.right .f8-interaction-box-inner-img img {
    max-width: 130px;
  }

  .f8-interaction-box.right .f8-interaction-box-inner-img img.rotate-svg-bottom,
  .f8-interaction-box.right .f8-interaction-box-inner-img img.rotate-svg-top {
    max-width: 50px !important;
  }

  .f8-prophylaxis-grpah-chart .y-axis-label:after {
    left: 44px;
  }

  .f8-prophylaxis-grpah-chart .y-axis {
    left: 11px;
  }

  .f8-prophylaxis-grpah-chart .grpah-chart-value {
    left: 100px;
    font-size: 16px;
  }

  .f8-prophylaxis-grpah-chart-two .y-axis-label:after {
    left: 58px;
  }

  .f8-prophylaxis-grpah-chart-two .label-top {
    font-size: 16px;
    margin-bottom: 1px;
  }

  .f8-interaction-box-graph .graph-years-title {
    left: -10px;
    font-size: 16px;
  }

  .falling-wrapper {
    flex-wrap: wrap;
    justify-content: center;
  }

  .d-flex.f8-interaction-box-inner {
    width: 100%;
    max-width: max-content;
    margin: 0 auto;
  }

  .f8-interaction-box.right {
    max-width: 651px;
    padding-left: 0;
    margin: 70px auto 0;
  }

  .bone-replace {
    max-width: 451px;
    margin: 0 auto;
  }

  .bone-joint-content .bone-joint-box {
    max-width: 280px;
  }

  .page-inner .f8-platelets p,
  .page-inner .f8-prophylaxis p,
  .page-inner .joint-bleeding-flex p {
    font-size: 16px;
    line-height: 25px;
  }

  .f8-interaction.dark .f8-interaction-box.right .f8-interaction-box-inner-img img,
  .joint-bleeding .joint-bleeding-box img,
  .joint-bleeding.right img {
    max-width: 170px;
  }

  .animate-sec-efficacy .slide-item-grid-item-box-data h5,
  .animate-sec-efficacy .slide-item-grid-item-desp,
  .animate-sec-efficacy .slide-last-item-grid-desp-box,
  .slide-last-item-grid-desp {
    font-size: 16px;
    line-height: 22px;
  }

  .animate-sec-efficacy .slide img {
    max-width: 150px;
  }

  .animate-sec-efficacy .slide-item-grid-item-box:after {
    max-width: 390px;
  }

  .efficacy-animate-sec .slide-item-data.slide-item-datas .slide-data-grid-right h6,
  .efficacy-animate-sec .slide-item-datas .slide-data-grid-right h6 {
    margin-bottom: 80px;
  }

  .f8-prophylaxis-grpah-chart.pupschart .label-axis-number {
    left: 12px;
  }

  section.produced-human-sec.factor-human-sec {
    padding: 160px 0 120px;
  }

  .f8-prophylaxis-grpah-chart#pupschart .y-axis {
    left: 105px;
  }

  #pups-proven-effective-sec .pups-proven-effective-img-left .zoom-animate-circle {
    top: -35%;
    right: -19%;
  }

  #pups-proven-effective-sec .cstm-animate .zoom-animate-circle .zoom-img {
    animation: 2s ease-in-out forwards zoomInproven;
  }

  @keyframes zoomInproven {
    0% {
      transform: scale(0.2);
      opacity: 0;
    }

    100% {
      transform: scale(1.3);
      opacity: 1;
    }
  }

  .antigenic-epitopes-sec .foot-note {
    left: calc(-100% - -90px);
  }

  .pups-produced-human-sec .pups-produced-human-next {
    margin-top: 200px;
  }

  section.produced-human-sec {
    padding: 50px 0 140px;
  }

  .nuprotect-study-sec .cstm-sub-desp {
    font-size: 22px;
    line-height: 30px;
    margin-bottom: 20px;
  }

  .nuprotect-study-sec .nuprotect-study-content-second .nuprotect-study-bottom-desp {
    margin-top: 70px;
  }

}

@media screen and (max-width: 991px) {
  header nav.navbar {
    padding: 13px 0;
  }

  header .navbar-light .navbar-toggler-icon {
    background-image: url("https://www.nuwiq.com/wp-content/uploads/2025/03/Menu-button.png");
    width: 24px;
    height: 24px;
  }

  .navbar-toggler[aria-expanded="true"] .navbar-toggler-icon {
    background-image: url(https://www.nuwiq.com/wp-content/uploads/2025/03/Menu-button-1.png);
    width: 24px;
    height: 24px;
  }

  header .navbar-light .navbar-toggler {
    border: 0;
    padding: 0;
  }

  header .navbar-nav {
    justify-content: center;
    align-items: center;
    padding: 100px 0 78px;
    height: 590px;
    overflow-y: auto;
  }

  header .navbar-nav ul.sub-menu {
    top: 0;
    position: relative;
    display: none !important;
    width: auto;
  }

  header .navbar-collapse.collapse.show {
    top: 75px;
    z-index: -1;
    background: #fff;
    width: 100%;
    left: 0;
    text-align: center;
    position: fixed;
    height: 100vh;
  }

  header .navbar-nav li.menu-item {
    padding: 22px 12px;
  }

  body.stopscroll {
    overflow: hidden;
  }

  .efficacy-animate-sec.slide-cstm-mobile-sec,
  .right.mobile-sec.animate-sec-efficacy .slide,
  .slide-cstm-mobile-sec .slide-item-data.slide-item-datas,
  .slide-cstm-mobile-sec .slide-item-datas,
  header .navbar-nav ul.sub-menu.menu-open {
    display: block !important;
  }

  .produced-human-sec .heading h2 sup {
    font-size: 24px;
    top: -10px;
  }

  .vial-size-infusion-sec .heading h2 sup {
    font-size: 23px;
    top: -11px;
  }

  section.video-sec .heading h2 sup {
    font-size: 23px;
    top: -12px;
  }

  .text-with-img-sec h2 sup {
    top: -8px;
    font-size: 18px;
  }

  .safety-tolerability-sec .heading h2 sup {
    font-size: 20px;
    top: -11px;
  }

  .efficacy-sec .heading h2 sup,
  .well-established-sec .heading p sup {
    font-size: 18px;
    top: -14px;
  }

  section.banner-sec .container {
    height: auto;
    position: static;
  }

  .banner-sec h1 {
    padding-top: 26px;
    font-size: 30px;
    line-height: 34px;
    letter-spacing: -0.36px;
    margin-bottom: 12px;
  }

  .produced-human-sec .heading h2,
  .text-with-img-sec h2,
  section.banner-sec .banner-sec-inner h1,
  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec .heading h2,
  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .heading h2 {
    font-size: 30px;
    line-height: 34px;
    text-align: center;
  }

  .text-with-img-sec h2 span {
    font-size: 24px;
    line-height: 33px;
  }

  .text-with-img-sec h3 {
    font-size: 26px;
    line-height: 26px;
    text-align: center;
  }

  .prophylaxis-data-sec .prophylaxis-data-content .prophylaxis-data-content-right h3,
  .text-with-img-sec h3 span {
    font-size: 20px;
    line-height: 26px;
  }

  .text-with-img-content {
    grid-template-columns: 1fr;
    text-align: center;
    padding-top: 20px;
  }

  .banner-tooltip,
  .produced-human-sec#flexible-dosing-section .produced-human-data-first {
    grid-template-columns: 1fr 1fr;
  }

  .factor-human-sec .antigenic-epitopes-mobile-sec .antigenic-epitopes-inner:nth-child(2) .antigenic-epitopes-left,
  .pups-text-with-img-sec .pups-text-with-img-content-left,
  .text-with-img-content-left {
    order: 2;
  }

  .text-with-img-content-right {
    order: 1;
  }

  section.text-with-img-sec .heading {
    max-width: 100%;
    margin-bottom: 70px;
    text-align: center;
  }

  .text-with-img-sec p {
    margin: 35px auto 66px;
    max-width: 699px;
    font-size: 16px;
    line-height: 24px;
  }

  .text-with-img-sec .text-with-img-list h4 {
    font-size: 18px;
    line-height: 22px;
    margin-bottom: 30px;
  }

  .text-with-img-sec .text-with-img-list li {
    font-size: 14px;
    margin-bottom: 13px;
    line-height: 20px;
  }

  .text-with-img-sec .text-with-img-list li span {
    font-size: 18px;
    line-height: 25px;
  }

  section.explore-sec .explore-sec-inner {
    gap: 20px;
    row-gap: 40px;
  }

  section.explore-sec .explore-sec-inner .explore-sec-img img {
    max-width: 160px;
    width: 160px;
    height: 160px;
  }

  section.explore-sec .explore-sec-inner h4 {
    font-size: 16px;
    line-height: 16px;
  }

  .text-with-img-sec .text-with-img-list ul {
    width: 100%;
    max-width: 485px;
    margin: 0 auto;
  }

  .group-slick-slider .item h4 {
    font-size: 24px;
  }

  .group-slick-slider .item h2,
  .group-slide-sec .portofolio p {
    font-size: 30px;
  }

  .animate-sec-efficacy .slide-item-grid-item-box-data h5,
  .animate-sec-efficacy .slide-item-grid-item-desp,
  .animate-sec-efficacy .slide-last-item-grid-desp-box,
  .efficacy-animate-sec .slide-data-grid .slide-data-grid-left p,
  .efficacy-animate-sec .slide-item-datas-desp,
  .produced-human-sec .heading,
  .prophylaxis-data-sec .heading,
  .slide-last-item-grid-desp,
  .vial-size-infusion-sec .heading,
  section.nuprotect-study-sec .heading {
    text-align: center;
  }

  .produced-human-sec .produced-human-data-first {
    gap: 15px;
    grid-template-columns: 1fr;
    margin-bottom: 53px;
  }

  .produced-human-content-left {
    order: 2;
    text-align: center;
    max-width: 700px;
    margin: 0 auto;
  }

  .demonstrates-effrctive-sec .demonstrates-effrctive-inner p,
  .efficacy-animate-sec .slide-item-data.slide-item-datas ul.slideitem-list li p,
  .efficacy-animate-sec .slide-item-datas ul.slideitem-list li p,
  .efficacy-sec h4,
  .eight-check-analysis .eight-check-analysis-inner .eight-check-analysis-list li p,
  .eight-check-analysis .eight-check-analysis-inner h4,
  .nuprotect-study-sec .nuprotect-study-content .nuprotect-study-content-left p,
  .produced-human-sec .produced-human-data-first .produced-human-content-left p,
  .pups-proven-effective-sec .pups-proven-effective-content p,
  .pups-text-with-img-sec .pups-text-with-img-content p,
  .safety-tolerability-sec .safety-tolerability-inner p,
  .well-established-sec .well-established-inner .well-established-data p {
    font-size: 16px;
    line-height: 24px;
  }

  section.video-sec .heading h2 {
    font-size: 30px;
    margin-bottom: 6px;
    line-height: 34px;
  }

  .vial-size-infusion-sec .heading p,
  section.video-sec .heading p {
    font-size: 18px;
    line-height: 22px;
  }

  #flexible-dosing-section .produced-human-content-right .zoom-animate-circle,
  .animate-sec-efficacy .slide-item-grid-item.left .slide-item-grid-item-desp br,
  .antigenic-epitopes-sec,
  .banner-tooltip .tooltip-box,
  .banner-tooltip .tooltip-data:after,
  .flexible-dosing-section .antigenic-epitopes-right .desp br,
  .section.animate-sec-efficacy,
  p br,
  section.banner-sec .banner-sec-inner a.btn {
    display: none;
  }

  .banner-tooltip .tooltip-data {
    opacity: 1;
    min-width: 100%;
    position: relative;
    left: unset;
    padding: 15px 18px 15px 54px;
    top: unset;
    border-radius: 4px;
  }

  .banner-tooltip .tooltip-data-1,
  .banner-tooltip .tooltip-data-2,
  .banner-tooltip .tooltip-data-3,
  .banner-tooltip .tooltip-data-4,
  .banner-tooltip .tooltip-data-5,
  .banner-tooltip .tooltip-data-6 {
    position: static;
  }

  .banner-tooltip {
    display: grid;
    gap: 36px;
  }

  .banner-tooltip .tooltip-data h4,
  .doosing-video-sec .reconstitution-instructions-btn p,
  .quick-links-sec .quick-links-boxs h5 {
    font-size: 14px;
    line-height: 16px;
  }

  .banner-tooltip .tooltip-data-img {
    width: 58px;
    min-width: 58px;
    height: 58px;
    right: auto;
    left: -14px;
  }

  .banner-tooltip .tooltip-data-3 .tooltip-data-img img {
    width: 52px;
    height: 52px;
  }

  section.banner-sec .banner-sec-inner {
    position: static;
    text-align: center;
    max-width: 540px;
    margin: 0 auto;
  }

  .banner-inner-content {
    max-width: 100%;
    margin-left: 0;
  }

  section.banner-sec .banner-sec-inner h2 {
    margin-bottom: 12px;
    text-align: center;
  }

  .quick-links-sec h4 {
    font-size: 9px;
    line-height: 12px;
    margin-bottom: 11px;
  }

  .quick-links-sec .quick-links-boxs {
    padding: 15px;
  }

  .quick-links-icon img {
    width: 25px;
    height: 25px;
    min-width: 25px;
  }

  .quick-download-link img {
    width: 21px;
    height: 21px;
    min-width: 21px;
    object-fit: contain;
  }

  .antigenic-epitopes-mobile-sec .antigenic-epitopes-inner {
    display: flex;
    gap: 37px;
    justify-content: center;
    align-items: center;
  }

  .antigenic-epitopes-mobile-sec .antigenic-epitopes-left img {
    width: 200px;
    height: 200px;
    object-fit: contain;
  }

  .antigenic-epitopes-mobile-sec .antigenic-epitopes-right p {
    font-family: Raleway;
    font-weight: 700;
    font-size: 16px;
    line-height: 24px;
    letter-spacing: 0.01px;
    color: #3a5664;
    max-width: 297px;
  }

  section.video-sec {
    padding: 77px 0 118px;
  }

  section.produced-human-sec {
    padding: 108px 0 0;
  }

  .produced-human-sec .heading p,
  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec .heading p,
  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .heading p {
    font-size: 18px;
    line-height: 22px;
    text-align: center;
  }

  .produced-human-sec .produced-human-content {
    margin-top: 30px;
  }

  .video-sec .video-sec-content {
    max-width: 580px;
    height: 412px;
  }

  .video-circle-layer {
    bottom: 0;
    left: 0;
  }

  .antigenic-epitopes-mobile-sec {
    display: flex;
    flex-direction: column;
    gap: 51px;
  }

  section.banner-sec .banner-sec-inner p {
    font-size: 16px;
    margin-bottom: 42px;
    max-width: 100%;
    line-height: 24px;
  }

  .pups-text-with-img-sec .pups-text-with-img-content {
    grid-template-columns: 1fr;
    text-align: center;
  }

  section.pups-text-with-img-sec {
    padding-top: 150px;
  }

  .pups-text-with-img-sec .circle-one {
    top: -140px;
    left: -133px;
  }

  .pups-text-with-img-sec .pups-text-with-img-content h2 {
    font-size: 30px;
    line-height: 32px;
  }

  .children-video-sec .heading h2,
  .efficacy-sec .heading h2,
  .produced-human-sec.pups-produced-human-sec .heading h2,
  .prophylaxis-data-sec .heading h2,
  .pups-proven-effective-sec .heading h2,
  .safety-tolerability-sec .heading h2,
  .vial-size-infusion-sec .heading h2,
  section.nuprotect-study-sec .heading h2,
  .animate-sec-efficacy .heading h2 {
    font-size: 30px;
    line-height: 34px;
  }

  .produced-human-sec.pups-produced-human-sec .heading p {
    font-size: 24px;
    line-height: 26px;
    max-width: 100%;
  }

  .children-video-sec .heading p,
  .efficacy-sec .heading p,
  .eight-check-analysis .heading p,
  .pups-proven-effective-sec .heading h3 {
    font-size: 24px;
    line-height: 26px;
  }

  .animate-sec-efficacy .slide-item-grid-item-box-data h5,
  .prophylaxis-data-sec .prophylaxis-data-content .prophylaxis-data-content-right .model-available,
  .prophylaxis-data-sec .prophylaxis-data-content .prophylaxis-data-content-right ul li,
  .pups-proven-effective-sec .heading p,
  section.disclaimer-sec .disclaimer-download,
  section.disclaimer-sec .disclaimer-inner-public .disclaimer-inner-public-data h6 {
    font-size: 16px;
    line-height: 20px;
  }

  .pups-proven-effective-sec .pups-proven-effective-img-left .circle-one {
    width: 655px;
    height: 655px;
    top: -61%;
    left: -320px;
  }

  .nuprotect-study-sec .nuprotect-study-content-inner.nuprotect-study-content-third .circle-two,
  .pups-proven-effective-sec .pups-proven-effective-img-left .circle-two {
    width: 492px;
    height: 492px;
  }

  .nuprotect-study-sec .nuprotect-study-content-inner.nuprotect-study-content-third .circle-three,
  .pups-proven-effective-sec .pups-proven-effective-img-left .circle-three {
    width: 376px;
    height: 376px;
  }

  section.pups-proven-effective-sec {
    padding: 90px 0;
  }

  section.nuprotect-study-sec .heading p {
    font-size: 24px;
    line-height: 26px;
    max-width: 566px;
    margin: 0 auto;
  }

  .nuprotect-study-sec .nuprotect-study-content .nuprotect-study-content-left {
    max-width: 282px;
  }

  .nuprotect-study-sec .cstm-sub-desp {
    font-size: 16px;
    line-height: 20px;
    margin-bottom: 42px;
  }

  .nuprotect-study-sec .nuprotect-study-content-inner {
    margin-bottom: 90px;
  }

  .nuprotect-study-sec .nuprotect-study-content-inner.nuprotect-study-content-third .circle-one {
    width: 655px;
    height: 655px;
    top: -73%;
  }

  section.eight-check-analysis {
    padding: 65px 0 71px;
  }

  .eight-check-analysis .heading h2 {
    font-size: 30px;
    line-height: 40px;
  }

  .eight-check-analysis .eight-check-analysis-inner .eight-check-analysis-list li span {
    width: 48px;
    height: 48px;
    min-width: 48px;
    padding: 10px;
    border-radius: 11px;
  }

  .eight-check-analysis .bottom-data,
  .nuprotect-study-content-btn a {
    flex-wrap: wrap;
  }

  .eight-check-analysis .bottom-data .bottom-data-text {
    flex: 0 0 100%;
    font-size: 16px;
    line-height: 20px;
  }

  section.safety-tolerability-sec {
    padding: 43px 0;
  }

  .safety-tolerability-sec .safety-tolerability-inner {
    gap: 36px;
    padding: 20px 20px 60px;
  }

  .well-established-sec .heading h2,
  section.demonstrates-effrctive-sec .heading h2 {
    font-size: 30px;
    line-height: 34px;
    margin-bottom: 7px;
  }

  .demonstrates-effrctive-sec .demonstrates-effrctive-inner h4 {
    padding: 18px 6px;
  }

  .demonstrates-effrctive-sec .demonstrates-effrctive-inner,
  .well-established-sec .well-established-inner {
    padding: 80px 10px;
  }

  .demonstrates-effrctive-sec .demonstrates-effrctive-inner img {
    margin: 50px auto;
  }

  .demonstrates-effrctive-sec .demonstrates-effrctive-inner img,
  .well-established-sec .well-established-inner .well-established-data img {
    width: 200px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom h6 {
    font-size: 18px;
    line-height: 22px;
    max-width: 538px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom li {
    font-size: 14px;
    line-height: 22px;
  }

  .vial-size-infusion-sec .heading h3 {
    font-size: 24px;
    line-height: 26px;
    margin-bottom: 37px;
  }

  .doosing-video-sec ul.video-list li {
    line-height: 22px;
    font-size: 16px;
  }

  .reconstitution-instructions-btn {
    max-width: 374px;
  }

  section.prophylaxis-data-sec {
    padding: 77px 0;
  }

  .prophylaxis-data-sec .prophylaxis-data-content .prophylaxis-data-content-right .model-available span {
    font-size: 20px;
  }

  .group-slide-sec .portofolio h1 {
    font-size: 24px;
    line-height: 34px;
  }

  .group-slide-sec .details {
    max-width: 90%;
  }

  .produced-human-sec .produced-human-content.pups-produced-human-next .antigenic-epitopes-left {
    margin-right: 0;
  }

  .produced-human-sec.pups-produced-human-sec .produced-human-content,
  section.produced-human-sec.adult-produced-human-sec .heading {
    margin-bottom: 70px;
  }

  section.produced-human-sec.adult-produced-human-sec .antigenic-epitopes-right p {
    text-align: left;
  }

  .well-established-sec .heading h2 sup {
    font-size: 20px;
    top: -12px;
  }

  section.demonstrates-effrctive-sec .heading h2 sup {
    font-size: 22px;
  }

  .planed-clinical-studies .heading h2 sup {
    font-size: 21px;
    top: -12px;
  }

  .completed-trials .heading h2 sup {
    font-size: 24px;
    top: -11px;
  }

  .quick-links-sec .quick-links-data {
    margin-top: 0;
  }

  section.banner-sec {
    background-size: 790px;
    padding: 80px 0 24px;
  }

  section.quick-links-sec {
    padding: 24px 0 53px;
  }

  section.text-with-img-sec {
    padding: 53px 0 70px;
  }

  #cstm-text-with-img-sec .circle-box-animate-text {
    top: 16px;
    left: 25%;
  }

  .text-with-img-sec .text-with-img-content-right .zoom-animate-circle {
    left: 148px;
    top: -20px;
  }

  .text-with-img-content .text-with-img-content-left {
    max-width: 100%;
  }

  .text-with-img-sec .text-with-img-content-left sup {
    top: -5px;
    font-size: 14px;
  }

  section.explore-sec {
    padding: 80px 0;
  }

  .produced-human-sec .heading h2 {
    max-width: 700px;
    margin: 0 auto 35px;
  }

  #home-human-cells .zoom-animate-circle {
    left: 111px;
    top: -8px;
  }

  .custom-footer .footer-list ul li a {
    padding: 13px 8px;
  }

  .banner-tooltip .tooltip-data-img img {
    width: 45px;
    height: 45px;
  }

  .pups-text-with-img-sec .circle-box-animate {
    left: 0;
    right: 0;
    margin: 0 auto;
  }

  .pups-text-with-img-sec .zoom-animate-circle {
    right: 0;
    top: -170px;
    left: 11px;
  }

  #pups-proven-effective-sec .pups-proven-effective-img-left img[alt="simoctocog-img"] {
    width: 228px;
  }

  section.produced-human-sec.pups-produced-human-sec {
    padding: 100px 0;
  }

  .nuprotect-study-content-right {
    margin-top: 50px;
  }

  .pups-text-with-img-sec.childern-banner-sec .circle-box-animate {
    top: 10px;
    left: 24px;
  }

  .pups-text-with-img-sec.childern-banner-sec .zoom-animate-circle {
    left: 40px;
    top: -154px;
  }

  .children-video-sec .video-content {
    height: 414px;
  }

  .efficacy-animate-sec .slide-item-data.slide-item-datas h2,
  .efficacy-animate-sec .slide-item-datas h2 {
    font-size: 30px;
    line-height: 34px;
    margin-bottom: 11px;
  }

  .efficacy-animate-sec .slide-item-data.slide-item-datas h5,
  .efficacy-animate-sec .slide-item-datas h5,
  .custom-content-box h4 {
    font-size: 18px;
    line-height: 22px;
    margin-top: 34px;
    margin-bottom: 40px;
  }

  .efficacy-animate-sec .slide-data-grid {
    grid-template-columns: 1fr;
  }

  @keyframes zoomIn {
    0% {
      transform: scale(0.2);
      opacity: 0;
    }

    100% {
      transform: scale(1.3);
      opacity: 1;
    }
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom li a {
    font-size: 14px;
    line-height: 20px;
    padding: 8px 13px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom li span {
    margin-right: 5px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom li span img {
    width: 44px;
    height: 44px;
    min-width: 44px;
  }

  .pups-text-with-img-sec.dosing-banner-sec .zoom-animate-circle {
    top: -150px;
  }

  .produced-human-sec#flexible-dosing-section.flexible-dosing-section .produced-human-data-first .produced-human-content-left {
    text-align: start;
    max-width: 591px;
    margin-left: auto;
  }

  .animate-sec-efficacy .slide-last-item-grid,
  .banner-tooltip .tooltip-data .download-btn,
  .nuprotect-study-content-btn.mobile-btn {
    display: block;
  }

  #pupschart.f8-prophylaxis-grpah-chart .y-axis,
  .platelets-describe .platelets-right .first {
    left: 0;
  }

  .f8-prophylaxis-grpah-chart.pupschart .y-axis-label:after {
    left: 57px;
  }

  .nuprotect-study-wrapper .right-content-title {
    left: 50px;
  }

  .nuprotect-study-svg #chart {
    width: 530px;
    height: 370px;
  }

  .all-inhibitors {
    font-size: 12px;
    line-height: 14px;
    top: 42px;
  }

  .nuprotect-study-wrapper .right-content-title h2 {
    font-size: 16px;
  }

  .f8-interaction-box-text p,
  .f8-interaction-box.right p,
  .f8-interaction-content .f8-interaction-box h6,
  .f8-interaction-content .f8-interaction-box-text h6,
  .f8-interaction-content .f8-interaction-box.right h6 {
    line-height: 18px;
    font-size: 14px;
  }

  .platelets-describe .platelets-left .first {
    right: 0;
  }

  .platelets-center-inner {
    gap: 40px;
  }

  .platelets-center .platelets-center-inner .platelets-center-first-arrow img,
  .platelets-center .platelets-center-inner .platelets-center-second-arrow img,
  .platelets-center .platelets-center-inner .platelets-center-third-arrow img {
    max-width: 30px;
    height: 30px;
    object-fit: contain;
  }

  .platelets-describe .platelets-box {
    padding: 12px 10px;
  }

  .f8-interaction.dark .f8-interaction-box .d-flex img,
  .f8-interaction.dark .f8-interaction-box.right .f8-interaction-box-inner-img img,
  .platelets-center .platelets-center-inner img {
    max-width: 100px;
  }

  .platelets-describe .platelets-left,
  .platelets-describe .platelets-right {
    margin: 20px 0 0;
  }

  .platelets-center .platelets-box:before {
    top: -63px;
  }

  .platelets-center-secound,
  .platelets-center-third {
    flex: calc(50% - 40px);
  }

  .platelets-center .platelets-center-inner .platelets-center-third-arrow {
    left: 42.6%;
  }

  .falling-item-outer {
    width: 100%;
  }

  .f8-prophylaxis-box.f8-prophylaxis-box-bottom {
    margin-top: 160px;
  }

  .f8-prophylaxis-box .f8-prophylaxis-box p {
    min-height: auto;
    margin: 0;
  }

  .f8-prophylaxis-grpah-chart .grpah-chart-value {
    left: 35%;
  }

  .f8-prophylaxis-grpah-chart .x-axis-higher-data {
    right: 130px;
  }

  .f8-prophylaxis-grpah-chart .y-axis {
    left: 90px;
  }

  .f8-interaction .f8-interaction-video,
  .safety-tolerability-sec .f8-interaction-video {
    height: 425px;
  }

  .f8-interaction-box .d-flex img,
  .joint-bleeding.right img {
    max-width: 220px;
  }

  .bone-joint-content .bone-joint-box h6 {
    font-size: 16px;
    line-height: 20px !important;
  }

  .page-inner .f8-platelets p,
  .page-inner .f8-prophylaxis p,
  .page-inner .joint-bleeding-flex p {
    font-size: 14px;
    line-height: 20px;
  }

  .f8-interaction.dark .f8-interaction-box.right .f8-interaction-box-inner-img {
    max-width: 265px;
  }

  .f8-interaction-box.right .f8-interaction-box-inner-img img.rotate-svg-bottom,
  .f8-interaction-box.right .f8-interaction-box-inner-img img.rotate-svg-top {
    max-width: 34px !important;
  }

  .animate-sec-efficacy .slide-item-grid {
    grid-template-columns: 1fr;
    gap: 40px;
  }

  .animate-sec-efficacy .slide-last-item-grid {
    justify-content: center;
    grid-template-columns: 1fr;
    margin: 0 auto;
    text-align: center;
  }

  .animate-sec-efficacy .slide-item-grid-item .slide-item-grid-item-desp {
    max-width: 400px;
  }

  .right.mobile-sec.animate-sec-efficacy {
    position: relative;
    background: url(https://www.nuwiq.com/nuwiq/wp-content/uploads/2025/06/BG-grid1.png) center/cover no-repeat;
    padding: 50px 80px;
    display: flex;
    flex-direction: column;
    gap: 80px;
  }

  .animate-sec-efficacy .slide-item-grid-item-desp,
  .animate-sec-efficacy .slide-item-grid-item.left .slide-item-grid-item-desp,
  .animate-sec-efficacy .slide-last-item-grid-desp-box {
    max-width: 424px;
    font-weight: 700;
    font-size: 14px;
    line-height: 20.4px;
    margin: 0 auto;
  }

  .antigenic-epitopes-mobile-sec .foot-note,
  .efficacy-animate-sec .slide-item-datas-desp {
    color: #95a6bf;
    font-family: Raleway;
    font-weight: 600;
    font-size: 12px;
    line-height: 16px;
    letter-spacing: 0;
  }

  .animate-sec-efficacy .slide-item-grid-item-desp {
    max-width: 378px;
  }

  .animate-sec-efficacy .slide-item-grid-item-desp span {
    font-weight: 800;
    font-size: 18px;
    line-height: 20.4px;
    letter-spacing: 0.01px;
  }

  .animate-sec-efficacy .slide img {
    max-width: 200px;
  }

  .animate-sec-efficacy .slide-last-item-grid-desp-box span {
    font-size: 18px;
    font-weight: 800;
  }

  .slide-last-item-grid .slide-last-item-grid-img {
    margin: 40px 0;
  }

  .right.mobile-sec.animate-sec-efficacy .slide-custom,
  .right.mobile-sec.animate-sec-efficacy .slide-item-grid-item-box-data {
    text-align: center;
    margin: 0 auto;
  }

  .right.mobile-sec.animate-sec-efficacy .slide-item-grid-item.left .slide-item-grid-item-desp {
    margin-bottom: 20px;
  }

  .efficacy-animate-sec.pin-section {
    display: none !important;
  }

  .efficacy-animate-sec .slide-item-data.slide-item-datas h3,
  .efficacy-animate-sec .slide-item-datas h3 {
    margin-bottom: 35px;
  }

  .efficacy-animate-sec .nupreviq-study-results a {
    padding: 14px 18px;
    font-size: 14px;
    line-height: 19px;
  }

  .efficacy-animate-sec .nupreviq-study-results svg {
    width: 21px;
    height: auto;
  }

  .efficacy-animate-sec.slide-cstm-mobile-sec .patients-lists,
  .efficacy-animate-sec.slide-cstm-mobile-sec .patients-lists-right {
    display: flex;
    align-items: center;
    gap: 10px;
    flex-direction: row-reverse;
  }

  .efficacy-animate-sec.slide-cstm-mobile-sec .patients-lists-right {
    flex-direction: unset;
  }

  .efficacy-animate-sec .slide-data-grid .slide-data-grid-right ul li {
    max-width: 476px;
    margin: 0 auto 30px;
  }

  section.disclaimer-sec .disclaimer-inner-public .disclaimer-inner-public-data a {
    padding: 25px 20px;
  }

  section.disclaimer-sec .disclaimer-inner-public .disclaimer-inner-public-data img {
    width: 20px;
  }

  section.disclaimer-sec .disclaimer-inner-content {
    padding: 20px 30px;
  }

  .produced-human-sec .produced-human-content.pups-produced-human-next .antigenic-epitopes-right p span {
    font-size: 33px;
    width: 70px;
    min-width: 70px;
    height: 70px;
  }

  .produced-human-sec .produced-cells .produced-cell-data h6 {
    font-size: 12px;
    line-height: 13px;
  }

  .antigenic-epitopes-mobile-sec .antigenic-epitopes-inner:nth-child(2n) .antigenic-epitopes-right p {
    text-align: right;
    max-width: 440px;
  }

  .produced-human-sec .produced-cell-video {
    left: calc(50% - 8%);
  }

  .produced-human-sec .produced-human-content.pups-produced-human-next .antigenic-epitopes-right p span img {
    max-width: 40px;
  }

  .flexible-dosing-section .antigenic-epitopes-mobile-sec .antigenic-epitopes-inner .antigenic-epitopes-left {
    flex: 0 0 200px;
    max-width: 200px;
  }

  .flexible-dosing-section .antigenic-epitopes-mobile-sec .antigenic-epitopes-inner .antigenic-epitopes-right {
    flex: calc(100% - 200px);
    max-width: calc(100% - 200px);
  }

  .flexible-dosing-section .antigenic-epitopes-right h4 {
    font-family: Raleway;
    font-weight: 700;
    font-size: 16px;
    line-height: 20px;
    letter-spacing: 0.01px;
    color: #159b80;
  }

  .flexible-dosing-section .antigenic-epitopes-right .desp {
    font-family: Raleway;
    font-weight: 700;
    font-size: 16px;
    line-height: 20px;
    letter-spacing: 0.01px;
    color: #3a5664;
  }

  .flexible-dosing-table-btn a {
    padding: 11px 12px;
    font-size: 12px;
    line-height: 13px;
    border-radius: 6px;
  }

  .flexible-dosing-table-btn a svg {
    margin-right: 11px;
    width: 20px;
    height: 20px;
  }

  .flexible-dosing-table .table>thead th {
    font-weight: 700;
    font-size: 12px;
  }

  .flexible-dosing-table .table>tbody td {
    font-size: 12px;
    line-height: 14px;
  }

  .flexible-dosing-table-btn {
    margin-bottom: 25px;
  }

  .demonstrates-effrctive-sec .demonstrates-effrctive-inner img,
  .safety-tolerability-sec .safety-tolerability-inner img,
  .well-established-sec .well-established-inner .well-established-data img {
    max-width: 200px;
    height: 200px;
  }

  .animate-sec-efficacy .slide-item-grid-item-box-data img,
  .animate-sec-efficacy .slide-last-item-grid-img img {
    max-width: 200px;
    margin: 0 auto 48px;
  }

  section.pups-text-with-img-sec.childern-banner-sec {
    padding-bottom: 20px;
  }

  section.efficacy-sec {
    padding: 20px 0 40px;
  }

  .nuprotect-study-content-btn {
    display: none;
    text-align: left;
  }

  #pups-proven-effective-sec .pups-proven-effective-img-left .zoom-animate-circle {
    top: -30%;
    right: -17%;
  }

  .flexible-dosing-section .produced-human-data-first .foot-note {
    order: 3;
  }

  .group-slide-sec .page {
    min-height: 60vh;
  }

  section.refernces-sec {
    padding: 50px 0;
  }
}

@media screen and (max-width: 767px) {
  .custom-footer {
    justify-content: center;
    flex-wrap: wrap;
  }

  header .navbar-collapse.collapse.show {
    top: 69px;
  }

  .custom-footer .footer-list ul,
  .nuprotect-study-content-btn a {
    flex-wrap: wrap;
    justify-content: center;
  }

  .quick-links-sec .quick-links-data a,
  section.disclaimer-sec .disclaimer-inner-public .disclaimer-inner-public-data {
    flex: 0 0 100%;
  }

  section.produced-human-sec.pups-produced-human-sec {
    padding: 70px 0;
  }

  .pups-text-with-img-sec .zoom-animate-circle .zoom-animation {
    height: auto;
  }

  .pups-text-with-img-sec .pups-text-with-img-content-right img {
    height: 400px;
  }

  .pups-text-with-img-sec .circle-box-animate {
    top: -2px;
  }

  #pups-proven-effective-sec .pups-proven-effective-img-left img[alt="simoctocog-img"] {
    width: 278px;
    margin: 0 auto;
  }

  #cstm-nuprotect-study-sec .nuprotect-study-content-right .zoom-animate-circle,
  #pups-proven-effective-sec .pups-proven-effective-img-left .zoom-animate-circle,
  .produced-human-sec .produced-cells .produced-cell-data h6 br {
    display: none;
  }

  .pups-proven-effective-sec .heading p {
    max-width: 266px;
    margin: 0 auto;
  }

  .pups-proven-effective-sec .pups-proven-effective-content {
    margin-top: 60px;
  }

  .pups-proven-effective-sec .nuprotect-study-btn {
    margin-top: 110px;
  }

  .pups-proven-effective-sec .nuprotect-study-btn .custom-button {
    width: 100%;
    max-width: 100%;
    justify-content: center;
    gap: 35px;
  }

  #cstm-nuprotect-study-sec .nuprotect-study-content,
  .animate-sec-efficacy .slide-item-grid-item-box,
  .produced-human-sec#flexible-dosing-section .produced-human-data-first {
    grid-template-columns: 1fr;
  }

  .flexible-dosing-table-btn,
  .nuprotect-study-content-btn,
  .produced-human-sec#flexible-dosing-section.flexible-dosing-section .produced-human-data-first .produced-human-content-left,
  div#disclaimerModal .popup-btn a,
  section.disclaimer-sec .disclaimer-download {
    text-align: center;
  }

  .eight-check-analysis .eight-check-analysis-center h2 {
    font-size: 30px;
    line-height: 34px;
    text-align: center;
  }

  .efficacy-animate-sec .slide-data-grid .slide-data-grid-left p,
  .efficacy-animate-sec .slide-data-grid .slide-data-grid-right ul li .list-title,
  .efficacy-animate-sec .slide-item-data.slide-item-datas .slide-data-grid-right h6,
  .efficacy-animate-sec .slide-item-datas .slide-data-grid-right h6,
  .eight-check-analysis .eight-check-analysis-inner .eight-check-analysis-list li p {
    font-size: 16px;
    line-height: 24px;
  }

  .eight-check-analysis .eight-check-analysis-inner .eight-check-analysis-list li {
    gap: 21px;
    margin-bottom: 24px;
  }

  .circle-box-animate svg,
  .circle-box-animate-text svg {
    width: 340px;
  }

  .pups-text-with-img-sec .zoom-animate-circle {
    top: -42px;
    left: 50%;
    transform: translateX(-50%);
    width: 100%;
    right: auto;
  }

  .efficacy-animate-sec .slide-data-grid .slide-data-grid-right ul li,
  .efficacy-animate-sec .slide-item-data.slide-item-datas ul.slideitem-list,
  .efficacy-animate-sec .slide-item-datas ul.slideitem-list,
  section.disclaimer-sec .disclaimer-inner-public {
    flex-wrap: wrap;
  }

  .efficacy-animate-sec .slide-item-data.slide-item-datas ul.slideitem-list li img,
  .efficacy-animate-sec .slide-item-datas ul.slideitem-list li img {
    max-width: 200px;
    margin: 0 auto;
  }

  #flexible-dosing-section .produced-human-content-right,
  .surgery-produced-human-sec-next .pups-produced-human-right-rotate .antigenic-epitopes-right {
    margin-right: 0;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom li a {
    font-size: 16px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom li span {
    margin-right: 25px;
  }

  .flexible-dosing-section .produced-human-content-left h4 {
    font-size: 24px;
    line-height: 30px;
  }

  #pupschart.f8-prophylaxis-grpah-chart .bar {
    width: 24px;
  }

  #pupschart.f8-prophylaxis-grpah-chart.pupschart .label-top {
    background: linear-gradient(135deg, #e8f1f9 0, #edf5fc 100%);
    width: 19px;
    height: 19px;
    font-size: 10px;
  }

  #pupschart.f8-prophylaxis-grpah-chart.pupschart .y-axis-label {
    margin-top: 26px;
  }

  #pupschart.f8-prophylaxis-grpah-chart.pupschart .blue-bar.thirty-one {
    height: 114px;
  }

  #pupschart .blinking-zero,
  .blinking-zero,
  .f8-interaction-box-graph .graph-info ul li,
  .f8-interaction-box-graph .graph-years-title,
  .f8-interaction-box-graph svg text,
  .f8-prophylaxis-grpah-chart .y-axis-label,
  .f8-prophylaxis-grpah-chart-two .label-top,
  .nuprotect-study-wrapper .right-content-title h2 {
    font-size: 10px;
  }

  #pupschart.f8-prophylaxis-grpah-chart.pupschart .blue-bar.forty-seven {
    height: 171px;
  }

  #pupschart.f8-prophylaxis-grpah-chart.pupschart .graph-info {
    top: 46px;
    left: 78px;
  }

  #pupschart.f8-prophylaxis-grpah-chart.pupschart .graph-info ul li {
    font-size: 10px;
    margin-bottom: 2px;
  }

  #pupschart.f8-prophylaxis-grpah-chart.pupschart .graph-info ul li span {
    width: 6px;
    height: 6px;
    margin-right: 7px;
  }

  @keyframes growBarthree {
    from {
      height: 0;
    }

    to {
      height: 114px;
    }
  }

  .f8-prophylaxis-grpah-chart.pupschart .graph-info {
    top: 58px;
    left: 80px;
  }

  #pupschart #yellow-bar-graph-three {
    height: 153px;
  }

  .nuprotect-study-graph-title .custom-button {
    font-size: 10px;
    line-height: normal;
    padding: 1px 10px;
    gap: 10px;
    border-radius: 4px;
  }

  #pupschart.f8-prophylaxis-grpah-chart .bar .label {
    font-size: 10px;
    line-height: 13px;
    left: -18px;
    min-width: 86px;
  }

  #pupschart.f8-prophylaxis-grpah-chart .bar .label img {
    width: 78px;
  }

  #pupschart.f8-prophylaxis-grpah-chart.pupschart .y-axis-label:after {
    left: 27px;
    width: 267px;
  }

  .f8-prophylaxis-grpah-chart.pupschart .bar.first-bar::after,
  .f8-prophylaxis-grpah-chart.pupschart .bar:empty::after {
    width: 2px;
    height: 7px;
  }

  .f8-prophylaxis-grpah-chart.pupschart .bar:empty::after {
    left: 13px;
  }

  .nuprotect-study-graph-title svg {
    width: 11px;
  }

  .nuprotect-study-graph-title {
    margin-bottom: 13px;
  }

  .nuprotect-study-svg #chart {
    width: 380px;
    height: 270px;
  }

  .nuprotect-study-wrapper .right-content-title {
    left: 0;
  }

  .all-inhibitors {
    font-size: 10px;
    line-height: 14px;
    top: 30px;
  }

  #pupschart.f8-prophylaxis-grpah-chart .y-axis {
    left: -35px;
    font-size: 10px;
  }

  .f8-prophylaxis-grpah-chart.pupschart.chart-container {
    gap: 5px;
    margin-left: 20px;
  }

  .factor-human-sec .antigenic-epitopes-mobile-sec .antigenic-epitopes-inner:nth-child(2) .antigenic-epitopes-left {
    order: 1;
  }

  .page-inner .bone-replace p {
    font-size: 14px;
    line-height: 20px;
  }

  .f8-interaction-box-graph .graph-info ul li .circle,
  .f8-interaction-box-graph .graph-info ul li .square {
    width: 9px;
    height: 9px;
  }

  .f8-interaction-box-graph .graph-age-title,
  .f8-prophylaxis-grpah-chart .x-axis-higher-data .x-axis {
    font-size: 10px;
    line-height: 11px;
  }

  .f8-prophylaxis-grpah-chart .bar {
    width: 36px;
  }

  .f8-prophylaxis-grpah-chart .x-axis-higher-data {
    right: 0;
  }

  .f8-prophylaxis-grpah-chart .x-axis-higher-data .x-axis-higher-icon {
    width: 70px;
    height: 70px;
  }

  .f8-prophylaxis-grpah-chart .x-axis-higher-data .x-axis-higher-icon svg {
    max-width: 30px;
  }

  .f8-prophylaxis-grpah-chart.chart-container {
    gap: 50px;
  }

  .f8-prophylaxis-grpah-chart .y-axis {
    left: 0;
    font-size: 10px;
  }

  .f8-prophylaxis-grpah-chart .y-axis-labels {
    margin-left: -15%;
  }

  .f8-prophylaxis-grpah-chart .y-axis-label:after {
    width: 174px;
    left: 20px;
  }

  .f8-prophylaxis-grpah-chart-two .y-axis-label:after {
    left: 29px;
  }

  .f8-prophylaxis-grpah-chart .y-axis-labels .y-axis-label:last-child:after {
    top: 9px;
  }

  .f8-prophylaxis-grpah-chart .bar .label {
    font-size: 10px;
    line-height: 12px;
    left: -12px;
  }

  .f8-prophylaxis-grpah-chart.pupschart .label-axis-number {
    left: 5px;
    bottom: -21px;
    font-size: 10px;
  }

  .f8-prophylaxis-grpah-chart .bar:before {
    width: 2px;
  }

  .platelets-describe {
    overflow-x: auto;
  }

  .platelets-describe .platelets-center.col {
    min-width: 280px;
  }

  .platelets-describe .platelets-left,
  .platelets-describe .platelets-right {
    flex: 0 0 300px;
    min-width: 300px;
  }

  .f8-interaction .f8-interaction-video,
  .safety-tolerability-sec .f8-interaction-video {
    height: 185px;
  }

  @keyframes growBartwo {
    from {
      height: 0;
    }

    to {
      height: 218px;
    }
  }

  .f8-prophylaxis-grpah-chart-two .blue-bar {
    height: 102px;
  }

  .f8-prophylaxis-grpah-chart .grpah-chart-value {
    left: 18%;
    font-size: 10px;
  }

  @keyframes growBar {
    from {
      height: 0;
    }

    to {
      height: 118px;
    }
  }

  .f8-prophylaxis-grpah-chart .blue-bar {
    height: 278px;
  }

  .right.mobile-sec.animate-sec-efficacy {
    padding: 50px 20px;
  }

  section.pups-text-with-img-sec {
    padding-bottom: 100px;
  }

  .efficacy-animate-sec .nupreviq-study-results a {
    width: 100%;
    display: flex;
    justify-content: space-between;
  }

  .efficacy-animate-sec .slide-data-grid .slide-data-grid-right ul li {
    align-items: flex-start;
    justify-content: center;
  }

  .efficacy-animate-sec .slide-data-grid .slide-data-grid-right ul li .list-count {
    font-size: 36px;
    width: 70px;
    height: 70px;
  }

  .efficacy-animate-sec.slide-cstm-mobile-sec .patients-lists,
  .efficacy-animate-sec.slide-cstm-mobile-sec .patients-lists-right {
    flex-direction: column;
    text-align: center;
  }

  .efficacy-animate-sec.slide-cstm-mobile-sec .patients-lists-right {
    flex-direction: column;
  }

  .efficacy-animate-sec.slide-cstm-mobile-sec .list-title.list-title-mobile {
    padding-top: 7%;
  }

  section.disclaimer-sec .disclaimer-inner-content h3 {
    font-size: 16px;
    line-height: 20px;
  }

  section.disclaimer-sec #nav-tabContent h4,
  section.disclaimer-sec #nav-tabContent p {
    font-size: 16px;
    line-height: 22px;
  }

  section.disclaimer-sec #nav-tabContent,
  section.disclaimer-sec .disclaimer-inner-content {
    padding: 15px;
  }

  div#disclaimerModal .disclaimer-download a,
  div#disclaimerModal .popup-btn a {
    flex-direction: column;
    justify-content: center;
    align-items: center;
  }

  #disclaimerModal .bottom-content p {
    font-size: 14px;
    line-height: 18px;
  }

  .children-video-sec .video-content {
    height: 190px !important;
  }

  #cstm-text-with-img-sec .circle-box-animate-text {
    top: 16px;
    left: calc(50% - 4px);
    transform: translateX(-50%);
  }

  .text-with-img-sec .text-with-img-content-right .zoom-animate-circle {
    left: 50%;
    top: -16px;
    transform: translateX(-50%);
    width: 100%;
  }

  .text-img-beaker {
    margin-left: calc(0% - -24px);
  }

  .antigenic-epitopes-mobile-sec .antigenic-epitopes-left img,
  .cstm-animate .zoom-animate-circle .zoom-img {
    margin: 0 auto;
  }

  @keyframes zoomIn {
    0% {
      transform: scale(0.2);
      opacity: 0;
    }

    100% {
      transform: scale(1.7);
      opacity: 1;
    }
  }

  .zoom-animate-circle .zoom-animation {
    animation: 4s forwards zoom-anim;
  }

  @keyframes zoom-anim {
    0% {
      transform: scale(0.2);
      opacity: 0;
    }

    100% {
      transform: scale(2.3);
      opacity: 1;
    }
  }

  .pups-text-with-img-sec img.cstm-banner-img {
    height: 330px;
  }

  .pups-text-with-img-sec .circle-box-animate svg {
    width: 290px !important;
  }

  .pups-text-with-img-sec.childern-banner-sec .circle-box-animate {
    top: 0;
    left: 0;
  }

  .pups-text-with-img-sec.childern-banner-sec .zoom-animate-circle {
    left: 50%;
    top: -22px;
  }

  .children-video-sec .video-btn a {
    width: 100%;
  }

  .pups-text-with-img-sec.dosing-banner-sec .zoom-animate-circle {
    left: 50%;
    top: -42px;
  }

  .produced-human-sec .produced-human-content.pups-produced-human-next .antigenic-epitopes-left {
    flex: 0 0 100%;
    margin: 0 auto;
    max-width: 100%;
  }

  .f8-prophylaxis-grpah-chart.pupschart .bar.last-bar:empty::after {
    left: 14px;
  }

  .f8-prophylaxis-grpah-chart.pupschart .bar.first-bar::after {
    left: 10px;
  }

  .nuprotect-study-sec .nuprotect-study-content .nuprotect-study-content-left img {
    max-width: 200px;
  }

  .nuprotect-study-content-btn svg {
    width: 20px;
    height: 20px;
  }

  .eight-check-analysis .bottom-data .bottom-data-text {
    font-size: 14px;
    padding: 15px 16px;
  }

  .pups-proven-effective-sec .nuprotect-study-btn .custom-button {
    padding: 12px 14px;
    font-size: 14px;
    line-height: 17px;
  }

  .nuprotect-study-sec .nuprotect-study-content-inner.nuprotect-study-content-third .nuprotect-study-content-right img {
    margin-left: 17px;
  }

  .doosing-video-sec ul.video-list {
    padding-left: 20px;
  }

  header nav.navbar img.image {
    width: 116px !important;
  }

  section.banner-sec {
    padding: 70px 0 24px;
  }

  section.prophylaxis-data-sec {
    overflow: hidden;
  }

  .prophylaxis-data-sec .prophylaxis-data-content .prophylaxis-data-content-left img {
    margin-left: 24px;
  }

  .produced-human-sec .produced-cells ul {
    flex-wrap: wrap;
    margin-bottom: 30px;
  }

  .produced-human-sec.home-human-cells ul li:last-child {
    max-width: 100%;
    flex: 0 0 100%;
  }

  .produced-human-sec ul li {
    justify-content: center;
  }

  .produced-human-sec .produced-cell-video svg {
    rotate: 90deg;
  }

  .flexible-dosing-section .antigenic-epitopes-mobile-sec .antigenic-epitopes-inner .antigenic-epitopes-left,
  .flexible-dosing-section .antigenic-epitopes-mobile-sec .antigenic-epitopes-inner .antigenic-epitopes-right {
    flex: 0 0 100%;
    max-width: 100%;
  }

  .f8-prophylaxis-grpah-chart.f8-prophylaxis-grpah-chart-two .blue-bar {
    height: 110px;
  }

  .animate-sec-efficacy .slide-item-grid-item-box-data img,
  .animate-sec-efficacy .slide-last-item-grid-img img {
    margin: 0 auto 48px;
  }

  .produced-human-sec .produced-cell-video {
    left: 50%;
    transform: translate(-50%, -50%);
  }

  .flexible-dosing-section .produced-human-data-first .foot-note {
    order: 3;
  }

  #post-1212 h1,
  .privacy-page h1 {
    font-size: 56px;
  }

  #post-1212 .entry-content {
    padding: 120px 40px 50px;
  }

  .page-content.privacy-page {
    padding: 120px 0 50px;
  }

  header .navbar-nav li.menu-item {
    padding: 12px;
  }

  header .navbar-nav li.menu-item a.nav-link {
    padding: 0;
  }
}

@media screen and (max-width: 575px) {
  section.banner-sec .banner-sec-inner p {
    line-height: 24px;
    margin-bottom: 20px;
  }

  .banner-tooltip,
  .demonstrates-effrctive-sec .demonstrates-effrctive-inner,
  .nuprotect-study-sec .nuprotect-study-content,
  .prophylaxis-data-sec .prophylaxis-data-content,
  .pups-proven-effective-sec .pups-proven-effective-content,
  .safety-tolerability-sec .safety-tolerability-inner,
  .well-established-sec .well-established-inner {
    grid-template-columns: 1fr;
  }

  section.quick-links-sec {
    padding: 107px 0 99px;
    background-color: #ebf4fb;
  }

  .quick-links-sec h4 {
    font-size: 16px;
    line-height: 28px;
    margin-bottom: 27px;
  }

  .quick-links-sec .quick-links-boxs {
    flex: 0 0 100%;
    padding: 24px;
  }

  .quick-links-icon img {
    width: 35px;
    height: 35px;
    min-width: 35px;
  }

  .quick-links-sec .quick-links-boxs h5 {
    margin-right: auto;
    padding-left: 20px;
  }

  .text-with-img-sec h3 {
    font-size: 24px;
  }

  .text-with-img-sec p {
    margin: 35px 0 55px;
    font-size: 16px;
  }

  section.text-with-img-sec {
    padding: 40px 0;
  }

  section.explore-sec {
    padding: 40px 0 70px;
  }

  section.explore-sec h3 {
    font-size: 18px;
    line-height: 26px;
    margin-bottom: 50px;
  }

  section.explore-sec .explore-sec-inner {
    flex-wrap: nowrap;
    overflow-x: auto;
  }

  section.explore-sec .explore-sec-inner .explore-sec-img img {
    max-width: 200px;
    width: 200px;
    height: 200px;
  }

  .group-slick-slider {
    padding: 112px 0 99px;
  }

  .group-slick-slider .item h4 {
    font-size: 26px;
    margin-bottom: 28px;
  }

  .group-slick-slider .item h2,
  .group-slide-sec .portofolio p {
    font-size: 28px;
  }

  section.produced-human-sec,
  .produced-human-sec.flexible-dosing-section {
    padding: 68px 0 95px;
  }

  .antigenic-epitopes-mobile-sec .antigenic-epitopes-inner {
    gap: 31px;
    flex-wrap: wrap;
  }

  .antigenic-epitopes-mobile-sec .antigenic-epitopes-right p {
    line-height: 24px;
    text-align: center;
  }

  .video-circle-layer {
    bottom: 70px;
    left: -130px;
  }

  .video-sec .video-sec-content {
    max-width: 100%;
    height: 200px;
  }

  section.video-sec .heading {
    margin-bottom: 38px;
  }

  section.video-sec .heading h2 {
    margin-bottom: 32px;
  }

  .pups-text-with-img-sec .circle-one {
    width: 585px;
    height: 585px;
    top: -120px;
    left: -123px;
  }

  .pups-text-with-img-sec .circle-two {
    width: 482px;
    height: 482px;
  }

  .pups-text-with-img-sec .circle-three {
    width: 386px;
    height: 386px;
  }

  section.pups-proven-effective-sec {
    padding: 69px 0 118px;
  }

  .nuprotect-study-sec .nuprotect-study-content-inner.nuprotect-study-content-third .circle-one,
  .pups-proven-effective-sec .pups-proven-effective-img-left .circle-one {
    display: none;
  }

  .antigenic-epitopes-mobile-sec .antigenic-epitopes-inner:nth-child(2n) .antigenic-epitopes-right p,
  .eight-check-analysis .eight-check-analysis-inner h4,
  .nuprotect-study-sec .nuprotect-study-content-inner.nuprotect-study-content-third .nuprotect-study-content-left p,
  .prophylaxis-data-sec .prophylaxis-data-content .prophylaxis-data-content-right h3,
  .pups-proven-effective-data-right,
  section.produced-human-sec.adult-produced-human-sec .antigenic-epitopes-right p {
    text-align: center;
  }

  .nuprotect-study-sec .nuprotect-study-content-inner {
    text-align: center;
    margin-bottom: 50px;
  }

  .nuprotect-study-sec .nuprotect-study-content .nuprotect-study-content-left {
    max-width: 100%;
    order: 2;
  }

  .eight-check-analysis .eight-check-analysis-content {
    padding: 55px 10px;
  }

  section.pups-text-with-img-sec {
    background-size: 190%;
  }

  .efficacy-sec .efficacy-inner-data {
    padding: 49px 19px 61px;
  }

  .efficacy-sec .heading h2 span {
    font-size: 30px;
    line-height: 34px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom ul {
    gap: 11px;
    flex-wrap: wrap;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom li {
    flex: 0 0 100%;
  }

  .prophylaxis-data-sec .heading p {
    font-size: 24px;
    line-height: 26px;
  }

  #post-1212 h3,
  .group-slide-sec .portofolio h1,
  .privacy-page h3 {
    font-size: 26px;
  }

  .antigenic-epitopes-mobile-sec .antigenic-epitopes-inner:nth-child(2n) .antigenic-epitopes-right,
  .antigenic-epitopes-mobile-sec .antigenic-epitopes-inner:nth-child(odd) .antigenic-epitopes-right {
    order: 1;
  }

  .produced-human-sec.pups-produced-human-sec .heading {
    margin-bottom: 80px;
  }

  section.produced-human-sec.adult-produced-human-sec.surgery-produced-human-sec-next .surgery-produced-human-bottom {
    margin: 110px auto 0;
  }

  .refernces-sec .refernces-inner li,
  .text-with-img-sec h3 span {
    font-size: 16px;
  }

  .refernces-sec .refernces-inner li span {
    font-size: 12px;
    width: 21px;
    height: 21px;
    min-width: 21px;
  }

  .refernces-sec .refernces-inner li a {
    display: inline-block;
    color: #3a5664;
  }

  .text-with-img-sec h2 span {
    font-size: 20px;
    line-height: 26px;
  }

  .text-with-img-content-right img {
    height: 310px;
  }

  .text-with-img-sec .text-with-img-content-right .circle-box-animate-text svg {
    width: 250px;
  }

  .text-with-img-sec .text-with-img-list li span,
  section.explore-sec .explore-sec-inner h4 {
    font-size: 16px;
    line-height: 18px;
  }

  section.explore-sec .explore-sec-inner {
    justify-content: flex-start;
    padding: 20px;
  }

  #home-human-cells .zoom-animate-circle {
    left: 0;
  }

  section.video-sec {
    padding: 82px 0 50px;
  }

  .nuprotect-study-svg #chart {
    width: 300px;
  }

  #post-1212 .entry-content {
    padding: 120px 20px 50px;
  }

  #post-1212 h1,
  .privacy-page h1 {
    font-size: 46px;
  }

  #post-1212 p,
  .privacy-page p {
    font-size: 14px;
  }

  section.children-video-sec {
    padding: 80px 0;
  }

  .factor-human-sec .produced-human-content {
    padding-top: 80px;
  }

  .refernces-sec .heading {
    margin-bottom: 40px;
  }

  .flexible-dosing-table .table>tbody td {
    min-width: 152px;
  }

  .flexible-dosing-table .table>tbody td:last-child {
    min-width: 220px;
  }
}

@media screen and (max-width: 400px) {
  .pups-text-with-img-sec .circle-box-animate svg {
    width: 266px;
  }

  .prophylaxis-data-sec .prophylaxis-data-content .prophylaxis-data-content-left img {
    margin-left: 22px;
  }
}

@media screen and (max-width: 360px) {
  .pups-text-with-img-sec .zoom-animate-circle {
    top: -15px;
  }

  .pups-text-with-img-sec img.cstm-banner-img {
    height: 300px;
  }

  .pups-text-with-img-sec .circle-box-animate svg {
    width: 253px !important;
  }

  .pups-text-with-img-sec.dosing-banner-sec .zoom-animate-circle {
    top: -20px;
  }
}